Navigation Links
Human Embryonic-Like Extracellular Matrix Significantly Inhibits Tumor Growth and Cancer Cell Proliferation
Date:6/17/2010

Studies of the human extracellular matrix (hECM) produced under proprietary conditions of hypoxia and suspension have demonstrated its ability to diminish or eliminate tumor load in melanoma, breast cancer, colon cancer and glioma, both in vitro and in vivo.

SAN DIEGO, CA (PRWEB) June 17, 2010 - Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn cells grown under embryonic conditions, will present findings tomorrow at the International Society for Stem Cell Research (ISSCR) Annual Meeting. Studies of the human extracellular matrix (hECM) produced under proprietary conditions of hypoxia and suspension have demonstrated its ability to diminish or eliminate tumor load in melanoma, breast cancer, colon cancer and glioma, both in vitro and in vivo.

Tumor growth was significantly inhibited across these cancer cell lines, with a 50-80% reduction in tumor weight seen in the tumor chorioallantoic membrane (tumcam) model (p<0.05) and a 70-90% reduction seen in subcutaneous mouse xenograft experiments (p<0.02). In studies of a carcinomatosis model established with a human colon carcinoma line, treatment with the hECM resulted in reduced tumor number and size, reduction of ascites, and, to date, a doubling in lifespan, as compared to untreated and cisplatin-treated mice.

"To see significant inhibition of multiple neoplastic cell lines, in multiple models, is a powerful indication of the future clinical potential of our embryonic-like extracellular matrix," said Dr. Mark Hubka, Histogen's Director of Clinical Affairs. "We are particularly excited about the potential utility of the hECM in rapidly progressing and debilitating cancers, such as carcinomatosis, where there are limited treatments that can offer an improvement in the quality and length of life."

Further studies of human colon adenocarcinoma have s
'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved  

Page: 1 2 3

Related biology technology :

1. Expiry of Hart-Scott-Rodino Waiting Period for JUVISTA(R) (Human TGF BETA 3)
2. New Initiative Has Shocking Effect: Thousands of Missourians with Abnormal Chromosome Structures Are Not Human
3. ExonHit Therapeutics: Allergan and ExonHits First Collaboration Compound to Begin Human Clinical Trials
4. Human Genome Sciences Announces $40 Million Milestone Payment Related to Albuferon(R) Development
5. Novocell Announces Discovery Linking Key Cancer Cell Signaling Pathways With Proliferation and Self-Renewal of Human Embryonic Stem Cells
6. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Thomas Weisel Partners Conference
7. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at BioCentury-Thomson Financial Investment Conference
8. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Bear Stearns Conference
9. Human Pheromone Sciences Enters Into Agreement to Reposition and Promote its Natural Attraction(R) Brand
10. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Merrill Lynch Conference
11. Premier Research Appoints Global Head of Human Resources
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Human Embryonic-Like Extracellular Matrix Significantly Inhibits Tumor Growth and Cancer Cell Proliferation 
(Date:7/10/2014)... Angeles, CA (PRWEB) July 10, 2014 ... and Bioanalytical techniques during 18-20 August, 2014 at Double ... critically review the recent developments in Analytical & Bioanalytical ... the globe. , Speaking on this occasion, Dr. Srinubabu ... Analytica Acta conference is a remarkable one in ...
(Date:7/10/2014)... Ind. , July 10, 2014 /PRNewswire/ ... its use of capnography for respiratory monitoring ... group of healthcare leaders in embracing state-of-the-art ... how effectively patients are breathing and can ... occurs. By measuring the amount of carbon ...
(Date:7/10/2014)... , July 10, 2014 /PRNewswire-iReach/ -- Tute ... interpretation, today announced an agreement with Lineagen, ... for Lineagen,s NextStep Dx PLUS.  Lineagen, ... and neurological disorders, currently offers FirstStep Dx ... testing service used by healthcare providers as ...
(Date:7/10/2014)... 2014 -- According to the International Atomic Energy ... comes from terrorists acquiring sufficient quantities of plutonium ... crude nuclear explosive device. The IAEA also notes ... involved gram-level quantities, which can be challenging to ... a new study appearing this week in the ...
Breaking Biology Technology:A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4Sensitive detection method may help impede illicit nuclear trafficking 2
... , , , For determining the optimal reagent for your cells , ... Contents , Kit Contents , Storage and Stability , ... Introduction , , , ... , , Effectene ...
... , QIAshredder spin columns are designed for simple and rapid homogenization , of cell ... , , Format: , ... , , Sample ... plant cell or tissue lysates, white blood cell lysates, , ...
... , , , Library siRNA is available against ... , Library siRNA is synthesised using patented TOM-Amidite chemistry, and , ... annealed, , desalted, and ready to use. A detailed certificate ... order. Library siRNAs are ready for transfection, , and are ...
Cached Biology Technology:Transfection Reagent Selector Kit Handbook 2Transfection Reagent Selector Kit Handbook 3Transfection Reagent Selector Kit Handbook 4Transfection Reagent Selector Kit Handbook 5Transfection Reagent Selector Kit Handbook 6Transfection Reagent Selector Kit Handbook 7Transfection Reagent Selector Kit Handbook 8Transfection Reagent Selector Kit Handbook 9Transfection Reagent Selector Kit Handbook 10Transfection Reagent Selector Kit Handbook 11Transfection Reagent Selector Kit Handbook 12Transfection Reagent Selector Kit Handbook 13Transfection Reagent Selector Kit Handbook 14Transfection Reagent Selector Kit Handbook 15Transfection Reagent Selector Kit Handbook 16Transfection Reagent Selector Kit Handbook 17Transfection Reagent Selector Kit Handbook 18Transfection Reagent Selector Kit Handbook 19Transfection Reagent Selector Kit Handbook 20Transfection Reagent Selector Kit Handbook 21Transfection Reagent Selector Kit Handbook 22Transfection Reagent Selector Kit Handbook 23Transfection Reagent Selector Kit Handbook 24Transfection Reagent Selector Kit Handbook 25Transfection Reagent Selector Kit Handbook 26Transfection Reagent Selector Kit Handbook 27Transfection Reagent Selector Kit Handbook 28Transfection Reagent Selector Kit Handbook 29Transfection Reagent Selector Kit Handbook 30QIAshredder Homogenizer 2
(Date:7/11/2014)... team of researchers from The Chinese University of Hong ... of wild soybean linked to salt tolerance, with implication ... soil. This study published online in Nature Communications ... information for crop improvement. , Soybean is an important ... selection, cultivated soybeans have less genetic diversities than their ...
(Date:7/11/2014)... group members to reduce aggression and gain access to ... grooming activities shows a certain pattern across the day. ... Biology Letters . , Grooming between individuals in ... motives. To be groomed has hygienic benefits and is ... can provide access to infants, mating opportunities and high ...
(Date:7/11/2014)... have explored two different ways that allow unprecedented ... the formation of oxygen molecules in photosynthesis. The ... journal Nature Communications . , "The new ... for water oxidation, which are key components for ... of solar energy in fuels like hydrogen, ethanol ...
Breaking Biology News(10 mins):BGI reports a novel gene for salt tolerance found in wild soybean 2Baboons groom early in the day to get benefits later 2Molecular snapshots of oxygen formation in photosynthesis 2
... are an important food source for fish and other aquatic ... this week in the Proceedings of the National Academy ... diets are supported by material that originates on land in ... to clarifying the role that watershed inputs play in aquatic ...
... BUFFALO, N.Y. -- An innovative, educational computing platform developed ... the cloud (remote, high-capacity, scalable servers) is helping UB ... new level. Soon, high-school and middle-school students will benefit ... by UB faculty members with a $250,000 National Science ...
... and Nanyang Technological University (NTU) are collaborating to enhance ... with oil., If successful, the wider application of the ... companies here to produce distilled water for their industrial ... at Singapore,s Jurong Island, which produce a lot of ...
Cached Biology News:Aquatic food web tied to land 2With cloud computing, the mathematics of evolution may get easier to learn 2With cloud computing, the mathematics of evolution may get easier to learn 3With cloud computing, the mathematics of evolution may get easier to learn 4memsys-NTU partnership to enhance water desalination technology 2
Biotin or fluorescent labels can be attached and the stoichiometry of protein labeling determined....
...
These macrocarriers are for the biolistic PDS-1000 He and Hepta systems. Supplied as 500 macrocarriers....
...
Biology Products: