Navigation Links
Huda Y. Zoghbi, MD, Receives $500,000 Gruber Neuroscience Prize
Date:6/15/2011

NEW YORK, June 15, 2011 /PRNewswire/ -- Huda Y. Zoghbi, MD, will receive the 2011 Neuroscience Prize of The Peter and Patricia Gruber Foundation for her pioneering work in unlocking genetic and molecular mysteries behind a number of devastating neurological disorders, including Rett syndrome, spinocerebellar ataxia type 1, and brain tumors called medulloblastomas. Her contributions have also greatly advanced our scientific understanding of autism, Parkinson's disease, and Alzheimer's disease.

Zoghbi, 56, is a professor of pediatrics, molecular and human genetics, neurology, and neuroscience at Baylor College of Medicine in Houston, Texas. She is also director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and a Howard Hughes Medical Institute investigator. Her work has inspired many researchers in the broad field of neurological disorders, and serves as an exemplar of how complex brain disorders can be better understood through basic genetics and molecular neuroscience.

She will receive the award November 13 in Washington D.C. at the Annual Meeting of the Society for Neuroscience and will deliver a lecture titled "Rett syndrome: Linking Epigenetics and Neuronal Plasticity."

Zoghbi began her career as a clinical pediatric neurologist, and much of her research has evolved from her early experiences with patients with rare neurological disorders. Her first major research breakthrough occurred in 1993 when she co-discovered a mutation in the gene ATXN1 that is responsible for spinocerebellar ataxia type 1, a deadly neurodegenerative disorder characterized by a progressive loss of movement. Scientists have subsequently related the discovery to other brain disorders, such as Huntington's, Alzheimer's, and Parkinson's diseases.

Professor Zoghbi is perhaps best known for her lab's 1999 identification of a mutation in the gene MECP2 that causes Rett syndrome, an autism spectrum disorder that leads seemingly healthy female toddlers to avoid eye contact, cease talking, engage in obsessive behaviors (such as constant hand-wringing), and develop other devastating symptoms. Until then, scientists were not sure this disorder was genetic. Further research by Zoghbi has uncovered much more about MECP2 mutations, including the finding that doubling levels of MECP2 can cause a host of neuropsychiatric features. These discoveries opened exciting new approaches to the study of autism and other psychiatric disorders.

Zoghbi's lab also identified Math1, a gene central to the formation of hair cells in the inner ear, which may lead to more effective treatments for certain types of deafness – especially age-related deafness and vestibular problems. Zoghbi and her team have also discovered that continuous activation of Math1 can cause granule cells in mice hindbrains to grow nonstop, which may be relevant to treating a common childhood brain tumor called medulloblastoma, and open up a new pathway for therapy in cancer.

The full release with Prize citation, other media materials, and additional background information on the Gruber Prizes can be found at our online newsroom: www.gruberprizes.org/Press.php.US Media Contact:

Foundation Contact:Cassandra Oryl

Bernetia Akin+1 (202) 309-2263

+1 (340) 775-4430pr@lunchboxcity.com

media@gruberprizes.org
'/>"/>

SOURCE The Peter and Patricia Gruber Foundation
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Biochemist and Geneticist Ronald W. Davis Receives $500,000 Gruber Genetics Prize for Pioneering Work in the Development of Biotechnologies that Have Significantly Advanced the Fields of Molecular Genetics and Genomics
2. Virginia Techs Kathy Lu receives Humboldt Foundation research award
3. Health Diagnostic Laboratory, Inc. (HDL, Inc.) Receives the Virginia Bioscience Company of the Year Award
4. MicroConstants China Receives Endorsement of OECD GLP Compliance
5. Verenium Receives CLARUS Award at MDB Capitals Bright Lights Conference 2011
6. Larta Institute Receives Award for National Institutes of Health Commercialization Assistance Program at 2011 Acquisition, Grants, and Small Business Symposium
7. Adeonas Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant
8. AquaStar Holdings, Inc.s Client Receives U.S. Patent 7,708,944 for Portable Capillary Sensor Technology
9. Cepheid Receives FDA Clearance for Xpert Flu, Delivering Simultaneous Detection and Differentiation of Flu A, Flu B, and 2009 H1N1 Strain
10. Eigen Receives Two Grant Awards from U.S. Department of Health & Human Services
11. Morphotek Receives Grant to Support Development of Therapeutic Antibodies against Biowarfare Agents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... (PRWEB) , ... February 09, 2016 , ... Tunnell Consulting, ... Based in Paris, he will focus on acquiring new accounts and work closely ... , “Fred brings to our European clients more than 15 years ...
(Date:2/9/2016)... ... February 09, 2016 , ... PharmApprove announced ... the National Organization for Rare Disorders (NORD). Dorman will lead PharmApprove efforts to ... heard throughout the drug regulatory review process. , “Adding Diane Dorman is just ...
(Date:2/9/2016)... and LONDON , February 9, 2016 ... bio tech replace paper and protect IP ... electronic laboratory notebook (ELN) will be rolled out in ... research and development (R&D) and protect valuable IP. Users will ... follow a specific researcher or experiment as part of the ...
(Date:2/9/2016)... LONDON , Feb. 9, 2016 /PRNewswire/ ... (PTP1B) Inhibitors-Pipeline Insights, 2016", report provides in ... their development activities around the Protein-Tyrosine Phosphatase ... the product profiles in various stages of ... Phase II, Phase III and Preregistration. Report ...
Breaking Biology Technology:
(Date:1/25/2016)...   Unisys Corporation (NYSE: UIS ) today announced ... International Airport, New York City , to help ... to enter the United States using passports ... pilot testing of the system at Dulles last year. The ... during January 2016. --> pilot testing of the ...
(Date:1/22/2016)... , Jan. 22, 2016 ... addition of the "Global Biometrics Market ... their offering. --> http://www.researchandmarkets.com/research/p74whf/global_biometrics ... "Global Biometrics Market in Retail Sector ... --> Research and Markets ( ...
(Date:1/20/2016)... --  MedNet Solutions , an innovative SaaS-based eClinical technology ... is pleased to announce the attainment of record-setting corporate ... of the company,s laser focus on (and growing international ... comprehensive, easy-to-use and highly affordable cloud-based technology platform. ... growth achievements in 2015 include: , Record ...
Breaking Biology News(10 mins):