Navigation Links
How to Enhance Scientific Intuition in Pharmaceutical R&D: the CBCD Highlights a Revolutionary New Technology
Date:11/27/2013

Rochester, NY (PRWEB) November 27, 2013

Rational Drug Design, which uses computers in designing new drug entities that bind with specific targets, did not resolve the productivity crisis in pharmaceutical R&D. “The current target based drug design approach is incomplete because most of the drugs developed by structure guided approaches have been shown to have serious toxic side effects.” This is according to a study published on October 14, 2009 in the European Journal of Pharmacology (2).

Furthermore, Jack Scannell, an analyst at Sanford C. Bernstein who covers European pharma said, “Only a minority of the most innovative drugs had their origins in target-based drug discovery; 17 out of 50. And of these 17, two drugs were eventually approved for indications that were entirely different to those that were intended at the start of the target based search.” The article was published on March 28, 2012 on Forbes.com (3).

The problem, however, is not computers. There are definite benefits in computer-aided drug design. But, in rational drug design, computers only process chemical information. They do not process biological information. In rational drug design, computers are a wonderful tool, but they are only as good as the intuition of the scientists that enter the input and interpret the output. The CBCD believes that today, the limiting factor in pharmaceutical R&D, and the cause of the productivity crisis, is the intuition of these scientists.

Let’s quantify intuition with the following measure. An increase in intuition is any increase in the foresight of the scientists. Or, in simple terms, the more scientists can look into the future, the better the scientist’s intuition is. Another example: Take two scientists. The one who says to the other ten years after the fact, “you were right” has less foresight, and less intuition.

Computer Intuition enhances scientific intuition. That is, it incre
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Blocked holes can enhance rather than stop light going through
2. Auxilium Announces Appointments to Enhance Leadership Team
3. Sigma-Aldrich Opens New Wuxi Packaging and Quality Control Facilities to Enhance Capabilities Serving China and Asia-Pacific Region
4. Elsevier Collaborates With Prophecy Healthcare to Enhance Its Staff Development Offerings for Healthcare Organizations
5. McLean Report on nanotechnology that may enhance medication delivery and improve MRI performance
6. Bio-inspired polymer synthesis enhances structure control
7. BGI Installs Roche GS FLX+ System to Enhance Long Read Sequencing Capabilities for Genome and Transcriptome Research
8. Generex Enhances Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine with Renowned Breast Cancer Researchers
9. Synteract Unveils New Branding at DIA 2012 to Support Enhanced Commercial Strategy
10. Spiral Flow(TM) Grafts Enhance Patient Outcomes - New Paper Published in the Prestigious Annals of Vascular Surgery
11. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... -- Research and Markets  has announced the addition of the ... report to their offering. This report analyzes ... Thousands by the following Product Segments: Media, Sera, and Reagents. ... Canada , Japan , ... Latin America . Annual estimates and forecasts are provided for ...
(Date:8/19/2014)... Cellgen Diagnostics today ... fund a corporate lab for its genetic-based medical ... is a critical component in the move from ... implementation of personalized medicine – a more predictive, ... Indiegogo contributions will support Cellgen’s intent to develop ...
(Date:8/19/2014)... La Jolla, CA (PRWEB) August 19, 2014 ... the toll Parkinson’s disease can take on an individual. ... tremoring extremities, decreased facial expression, problems swallowing and severe ... due to the dying off of dopamine producing neurons ... retain themselves from a disease that slowly and progressively ...
(Date:8/19/2014)... Aug. 19, 2014 Research ... of the "Spectroscopy Equipment and Accessories ... to their offering. This ... Equipment and Accessories in US$ Thousands by ... spectrophotometers, Raman Spectrometers, NMR-EPR Spectrometers, Near Infrared ...
Breaking Biology Technology:Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 2As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 3Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2
... ability to drive clients, success in managed care, ... Group, a,full-service managed market agency focused on securing ... of Dan Renick, RPh,as Managing Partner. Renick will ... biotech clients, including GlaxoSmithKline,sanofi-aventis, and Forest Laboratories., ...
... Abbott will present,at the Goldman Sachs Twenty-Ninth ... Thomas C. Freyman, executive vice president,finance and chief ... at 3:20 p.m. Central time., A live ... through,Abbott,s Investor Relations Web site at http://www.abbottinvestor.com ...
... China, May 28 /Xinhua-PRNewswire-FirstCall/ -- 3SBio Inc.,(Nasdaq: ... focused on researching,developing, manufacturing and marketing biopharmaceutical ... Chief Operating Officer, and,Kevin Teo, Chief Financial ... Annual Global Healthcare Conference in Dana Point, ...
Cached Biology Technology:Dan Renick, RPh, Joins The Hobart Group as Managing Partner 2
(Date:8/20/2014)... In leaves, photosystem 1 (PS1) absorbs light and ... of carbon dioxide to biomass. Photovoltaic devices, mostly ... light but produce electricity. One approach for the ... replacing the semi-conductor with the isolated membrane protein ... isolates a highly stable PS1 from thermophilic cyanobacteria ...
(Date:8/19/2014)... China,s increasing caesarean section rate, suggests a new commentary ... Journal of Obstetrics and Gynaecology (BJOG) . , China ... the world. Of 16 million babies born in 2010, ... is not known, the current Chinese language literature on ... from 36% to 58%. However, before the 1980s, the ...
(Date:8/19/2014)... Wind and ... amount of electricity is to be produced with renewable energy ... stored during productive periods so that these fluctuations can be ... for the purpose. Science and industry are therefore working on ... that used to be too expensive or unsophisticated to be ...
Breaking Biology News(10 mins):A semi-artificial leaf faster than 'natural' photosynthesis 2Is China's 50 percent cesarean section delivery rate too high? 2Is China's 50 percent cesarean section delivery rate too high? 3Asian inventions dominate energy storage systems 2Asian inventions dominate energy storage systems 3
... (March 28, 2011)Understanding that angioplastya medical treatment used by ... and chest to improve blood flowis safe may encourage ... for individuals with multiple sclerosis, say researchers at the ... Chicago, Ill. "Angioplastythe nonsurgical procedure of threading a ...
... March 28, 2011 University of Utah scientists used ... and toadfish inner-ear cells send signals to the brain. ... and lead to devices to restore vision, maintain balance ... to talk to the brain with optical infrared pulses ...
... JOLLA, CA Over the last years, two teams of ... model of how a powerful DNA repair complex works. Now, ... molecular motor inside the complex functions findings they say ... to cystic fibrosis. In a paper published in an ...
Cached Biology News:Interventional radiologists advance MS research: Vein-opening treatment safe 2Interventional radiologists advance MS research: Vein-opening treatment safe 3Interventional radiologists advance MS research: Vein-opening treatment safe 4Will we hear the light? 2Will we hear the light? 3Will we hear the light? 4Will we hear the light? 5Structure of DNA repair complex reveals workings of powerful cell motor 2Structure of DNA repair complex reveals workings of powerful cell motor 3Structure of DNA repair complex reveals workings of powerful cell motor 4
...
Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...
Experion HighSens chips are the microfluidic chips used to perform high-sensitivity RNA analysis (picogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to ru...
...
Biology Products: