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How now, inside the cow: Nearly 30,000 novel enzymes for biofuel production improvements
Date:1/27/2011

that had been assembled in silico. "The single cell data made us confident that what we saw was real," Hess said. "Otherwise we'd have computational data only, which would have made our work much, much less convincing."

This pioneering work, led by the JGI and its collaborators, illustrates that with large scale sequencing capabilities combined with large scale data analysis and computational capabilities and state-of-the-art next generation single cell genomics, researchers can now explore a vast array of cellulosic degrading enzymes from new microbes not tied to the ability to grow them in culture. This may therefore reduce the vast space of "microbial dark matter" that has up to now been difficult to explore. Additionally, the approach used here could be readily extended to searches for other microbial enzyme capabilities of relevance to other DOE missions.


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Contact: David Gilbert
degilbert@lbl.gov
925-296-5643
DOE/Joint Genome Institute
Source:Eurekalert  

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