Hologic Announces First Quarter Fiscal 2008 Operati...(exclude the increase in cost of revenues...)

write-up of acquired Cytyc inventory sold during the first quarter of

fiscal 2008.

(4) To exclude the non-cash expense associated with the write-off of

certain intangible assets acquired from Cytyc in the first quarter of

fiscal 2008.

(5) To exclude the non-cash expense associated with the write-off the

acquired in-process research and development related to the

acquisition of Cytyc in the first quarter of fiscal 2008.

(6) To reflect the tax effect at an estimated effective rate of 36% of

adjustments (1), (2), (3) and (4) above.

(7) To reflect the tax effect at an estimated effective rate of 38% of

adjustment (1) and (2) above.

Contact:

Glenn P. Muir Frances Crecco

Executive Vice President & CFO Director, Investor Relations

Hologic, Inc. Hologic, Inc.

(781) 999-7300 (781) 999-7377