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Histogen Creates PUR Biologics, a Joint Venture Developing Next-Generation, Biologic Solutions in Orthopedic Applications
Date:3/11/2013

ll stages of development and commercialization. The Company’s first research and development efforts will be in the area of bone regeneration, which has potential benefit in a number of orthopedic applications.

The joint venture will be managed and funded by Histogen’s partner group, made up of experts from the surgery and medical device industries. Ryan Fernan, CEO of the newly-created PUR Biologics, has spent more than a decade in medical sales and management, including bringing OC Surgical from a fledgling medical device distributorship to a multi-million dollar orthopedic business during his time as President of the Company. PUR Biologics’ management and investment group has a proven track record synergistically packaging technologies and advancements in surgery to serve unmet medical needs.

"We are extremely excited to have access to Histogen's groundbreaking scientific platform,” said Ryan Fernan. “Coupled with our extensive experience in product development, sales, and distribution, this will be a powerful relationship that will fuel development of much needed innovation in this space."

The creation of PUR Biologics allows Histogen to support the research required to bring its biologic products toward commercialization in the rapidly growing multi-billion dollar orthopedic market, while continuing to dedicate resources to the Company’s other promising aesthetic and therapeutic programs.

“Histogen’s preliminary studies have shown that our human CCM and ECM materials support stem cell growth and differentiation into bone and other structural tissues, making orthopedics a promising and exciting area of research for our products,” said Dr. Gail K. Naughton, Histogen CEO and Chairman of the Board. “This joint venture provides Histogen the opportunity to see its innovative cell-derived products make strides in the large and important orthopedic market, while continuing to focus on development of its hair growth, skin
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