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Highly Sensitive and Quantitative Analytical Performance is Translational for Clinical Utility of Cell-Free Tumor DNA Diagnostics
Date:8/26/2014

l sensitivity of the PCM platform, results from a blinded retrospective study of urine samples from colorectal cancer patients were reported, which demonstrated both high sensitivity and concordance to tissue biopsies for the detection of specific KRAS mutations in urine.  Summary results from other blinded, prospective clinical studies demonstrated high clinical sensitivity for the detection of BRAF V600E mutations, with highly significant correlation between treatment responses and changes in measured levels of BRAF V600E over time from urine samples of patients with various metastatic cancer types. 

"The reported strong analytical performance of our precision monitoring platform is enabling translation to high clinical sensitivity and quantitative monitoring of tumor mutations from urine samples of cancer patients," stated Mark Erlander, Ph.D., chief scientific officer of Trovagene. "We continue to conduct clinical studies using our PCM platform through our numerous collaborations with academic medical centers and integrated healthcare networks to demonstrate utility of cell-free tumor diagnostics and to improve the standard of care for cancer patients."

About Trovagene, Inc.

Headquartered in San Diego, California, Trovagene is leveraging its proprietary technology for the detection and monitoring of cell-free DNA in urine.  The company's technology detects and quantitates oncogene mutations in cancer patients for improved disease management. Trovagene's precision cancer monitoring platform is designed to provide important clinical information beyond the current standard of care, and is protected by significant intellectual property including multiple issued patents and pending patent applications globally.

Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statem
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SOURCE Trovagene, Inc.
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