Navigation Links
High-strength silk scaffolds improve bone repair
Date:4/30/2012

ss and surface roughness that enhanced human mesenchymal stem cell differentiation compared to control silk sponges. In combination with inherent silk fiber strength, compact fiber reinforcement enhanced compressive properties within the scaffolds.

"By adding the microfibers to the silk scaffolds, we get stronger mechanical properties as well as better bone formation. Both structure and function are improved," said David Kaplan, Ph.D., chair of biomedical engineering at Tufts University. "This approach could be used for many other tissue systems where control of mechanical properties is useful and has broad applications for regenerative medicine."

Other authors on the paper were Biman B. Mandal, former post doctoral associate in the Department of Biomedical Engineering at Tufts and now in the Department of Biotechnology, Indian Institute of Technology; visiting biomedical engineering student Ariela Grinberg, who recently completed her degree in the Department of Tissue Engineering, Cell Therapy and Regenerative Medicine at the National Institute of Rehabilitation, Mexico; and Eun Seok Gil and Bruce Panilaitis, research associate and research assistant professor respectively in the Department of Biomedical Engineering at Tufts.

The Tufts scientists used a novel approach to manufacturing the silk microfibers: applying alkaline hydrolysis (the use of alkali chemicals to break down complex molecules into their building blocks). This greatly reduced the time and cost of making the microfibers in a variety of sizes. Microfibers ranging from 10 to 20 um were obtained in one minute, compared with production of 100 um plus size fibers after 12 minutes of conventional processing.

Although significant improvements in compressive properties were observed in the silk composite scaffolds, values were still significantly lower than that of stronger native bone. The Tufts researchers suggest that such scaffolds can play a valuable role as tem
'/>"/>

Contact: Kim Thurler
kim.thurler@tufts.edu
617-627-3175
Tufts University
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Self-assembling polymer arrays improve data storage potential
2. Beaumont Doctors Invention Improves Cataract Surgery Outcomes
3. Early-Bird Registration Ends this Week for 10th Annual Quality Excellence Conference: How Process Improvement Leaders Produce Profits in Recessions
4. Carilion Clinic Invests in Sight Saving Technology to Improve Patient Care: Carilion Clinic Teams Up with Retasure
5. Germicidal UVC Lights Improve Clinical Pregnancy Rates for IVF Lab, New Study Finds
6. Sanofi Aventis : New Study Results Support the "Basal Plus" Strategy With LANTUS(R) and APIDRA(R) to Improve Blood Sugar Control in Patients With Type 2 Diabetes
7. Enobia Pharma Presents PreClinical Data Showing ENB-0040 Significantly Improved Survival and Healed Skeletal Manifestations of Severe Hypophosphatasia in Mice
8. Global Psychiatrists Unite to Improve Services in Mental Health
9. Kelly Osbourne and International Health Groups Call for Improved Education on Choices and Usage of Contraception
10. Commonwealth Care Alliance Selects Casenet To Unify Patient Information and Improve Care for Massachusetts Members
11. Finesse Solutions Launches Improved E-Store for Sensors and Transmitters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2015)... --  Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ) ... 35 th Annual Health Care Conference on Tuesday, March ... .  Lexicon management will provide an overview of Lexicon,s ... the presentation will be available through Lexicon,s website at ... available at www.lexpharma.com until April 3, 2015. ...
(Date:2/26/2015)... SAN FRANCISCO, Calif. , Feb. 26, 2015 /PRNewswire/ ... the treatment of cancer, today announced that Sean ... a corporate overview at the upcoming Cowen and Company ... Boston . Dr. McCarthy,s presentation will take ... About CytomX Therapeutics CytomX Therapeutics develops ...
(Date:2/26/2015)... Caris Life Sciences® today announced the ... Cancers Symposium in Orlando, Fla. ... profiling. Both studies utilized Caris Molecular Intelligence™, the ... biomarkers that shed light on potential treatment strategies ... cancer (SCBC). In one study, ...
(Date:2/25/2015)... Technologies Inc. (TSX-V: RTI) (the "Corporation") announced today that ... quarter of its fiscal year ended March 31, 2015. ... the CEO & CFO certifications for the three and ... on www.SEDAR.com . CFO ... pleased to announce the appointment of Prakash Hariharhan as ...
Breaking Biology Technology:Lexicon To Present At The Cowen 35th Annual Health Care Conference 2Tumor Profiling of Metastatic Prostate and Small Cell Bladder Cancers with Caris Molecular Intelligence Yields Insights into Novel and Conventional Therapeutic Options 2Tumor Profiling of Metastatic Prostate and Small Cell Bladder Cancers with Caris Molecular Intelligence Yields Insights into Novel and Conventional Therapeutic Options 3Tumor Profiling of Metastatic Prostate and Small Cell Bladder Cancers with Caris Molecular Intelligence Yields Insights into Novel and Conventional Therapeutic Options 4Tumor Profiling of Metastatic Prostate and Small Cell Bladder Cancers with Caris Molecular Intelligence Yields Insights into Novel and Conventional Therapeutic Options 5Radient Technologies Inc. Releases Third Quarter Results and Appoints New Interim CFO 2
... is Japan. In this column, I have covered different aspects ... 3/28/05). I had the good fortune to return to Japan ... a three-year hiatus. , ,My last visit there was ... sister city relationship, which had started in Chicago and culminated ...
... Wis. - GE Healthcare , the $15 billion ... U.S. Food and Drug Administration clearance for its heart-imaging ... 70 percent per scan. , ,The technology is based on ... multiple X-ray images together to create a three-dimensional image of ...
... Wis. - Cyber threats are becoming more sophisticated ... companies aren't acting on the threats, a panel of ... on the state of information security during the annual ... technology executives continued to emphasize the necessary balance between ...
Cached Biology Technology:Japan on the rebound: Implications for Midwest 2Japan on the rebound: Implications for Midwest 3Japan on the rebound: Implications for Midwest 4Japan on the rebound: Implications for Midwest 5Japan on the rebound: Implications for Midwest 6Japan on the rebound: Implications for Midwest 7Japan on the rebound: Implications for Midwest 8Japan on the rebound: Implications for Midwest 9FDA approves GE's heart-imaging technology 2Companies still neglect network security 2
(Date:2/5/2015)... Jan. 28, 2015 Research and Markets ... of the "Global Biometrics Market (2014-2020): Market ... Countries " report to their offering. , ... Asia-Pacific is anticipated to overtake ... to increasing government spending towards IT security, government ...
(Date:1/22/2015)... FindBiometrics, the leading source of biometrics industry news, interviews and ... "When we launched FindBiometrics 12 years ago the ... founder and CEO of FindBiometrics. "Now it,s maturing very quickly. ... players on a very broad scale.  We are known for ...
(Date:1/22/2015)... , Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... market, reports on the recent success of the Wocket™ smart wallet at ... Wocket smart wallet was named as one of the "11 Hot Products ... Best Products Launched At CES So Far" by Newseveryday.com and "The top ...
Breaking Biology News(10 mins):Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 2Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 3Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3
... is available in German . ... In the wild Arabidopsis thaliana uses the same ... its size in half as found in semi-dwarf varieties of rice and ... various plant species apparently fall back on the same genes in their ...
... abdominal surgery may paradoxically prolong a patient,s suffering, doubling ... to recover from the surgical pain, according to researchers ... team from CU-Boulder,s Department of Psychology and Neuroscienceled by ... Galer, a professional research assistantwas able to identify the ...
... solar panels, wringing every drop of energy from as ... has sent chemistry, materials science and electronic engineering researchers ... photovoltaic devices, but existing techniques are now running up ... Now, researchers from the University of Pennsylvania ...
Cached Biology News:The secret of short stems 2The secret of short stems 3Using morphine after abdominal surgery may prolong pain, CU-Boulder researchers find 2Penn and Drexel team demonstrates new paradigm for solar cell construction 2Penn and Drexel team demonstrates new paradigm for solar cell construction 3Penn and Drexel team demonstrates new paradigm for solar cell construction 4Penn and Drexel team demonstrates new paradigm for solar cell construction 5
... Plant Leaf DNA Purification Kit is designed for ... leaf tissue. The protocol can be completed in ... up to obtain larger amounts of DNA. The ... restriction digestion, and Southern blotting. The MasterPure Kit ...
Caspase Activity Detector, SR-VAD-FMK Kit , 100 tests Consult technical datasheet for details....
HistoScan AP Universal Goat Kit...
...
Biology Products: