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Heptares Grants Shire an Exclusive Worldwide Licence to Develop and Commercialise Novel Drug Candidate for CNS Disorders
Date:3/20/2012

includes proprietary technologies for engineering stabilised GPCRs in their natural pharmacological conformations, identifying previously unknown chemistries for GPCR protein-drug interactions, and deploying advanced fragment-based approaches to GPCR target space for the first time. Using this approach, we are generating a broad pipeline of drug candidates for serious CNS and metabolic disorders, including Alzheimer's disease, Parkinson's disease, schizophrenia, autism, anxiety & depression, chronic insomnia, addiction and diabetes.  For more information, please visit http://www.heptares.com.

References

  1. Langmead, C. et al. (2012) J. Med. Chem. DOI: 10.1021/jm201455y. Published online: January 17, 2012
  2. Congreve, M. et al. (2012) J. Med. Chem. DOI: 10.1021/jm201376w. Published online: January 5, 2012
  3. Zhukov, A. et al. (2012) J. Med. Chem., 2011, 54 (13), pp 4312-4323

Contact Information

Citigate DeweRogerson (for Heptares)
Mark Swallow, Chris Gardner
+1 857-222-4586
dan.grau@heptares.com

+44 (0)20-7282-2948
mark.swallow@citigatedr.co.uk

Heptares Therapeutics Ltd

Malcolm Weir, Chief Executive Officer (UK)
+44 (0)1707-358-629
malcolm.weir@heptares.com

Dan Grau, President (USA)
+1-857-222-4586
dan.grau@heptares.com



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