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Hemoglobin A1c Testing Markets
Date:3/25/2013

3-2008 25
Figure 2.11: Relative Risk of Diabetes Complications by Mean HbA1c 27
Figure 2.12: Mean Diabetes Healthcare-related Expenditures Per Adult (20-79
Years) with
Diabetes (USD), 2011 34
Figure 3.1: Worldwide HbA1c Testing Market, 2008-2017 40
Figure 3.2: U.S. HbA1c Testing Market, 2008-2017 41
Figure 3.3: Global HbA1c Self-Testing Market, 2008-2017 42
Figure 4.1: Non-Enzymatic Glycation of Hemoglobin 49
Figure 4.2: Boronate Affinity Binding of Glycated Protein 51
Figure 4.3: Comparison of HbA1C and Blood Glucose Measurements over a Four-Day
Period 55
Figure 4.4: Range of Variation in HbA1c Assay 62
Figure 4.5: Range of Variation in the FPG Assay 62
Figure 7.1: CLIA Laboratories by Certificate Types 94

INDEX OF TABLES

Table 2.1: Regional Estimates of the Number of Diabetes (20-79 Years), 2011 and
2030 14
Table 2.2: Countries with the Largest Numbers of Diabetics, 2011 15
Table 2.3: Countries with the Largest Estimated Numbers of Diabetics, 2030 15
Table 2.4: Worldwide Undiagnosed Diabetes in Adults (20-79 Years) by Region and
Income Group, 2011 16
Table 2.5: U.S. Population of Diabetics (Diagnosed and Undiagnosed) Aged 20
Years or Older, 2010 17
Table 2.6: U.S. Incidence of Diagnosed Diabetes by Age, 2009 19
Table 2.7: Ten Leading Diagnoses for Co-Morbid Chronic Diseases in the U.S. 26
Table 2.8: Odds Ratio of Progression to Complications Associated with Type 2
Diabetes 27
Table 2.9: Prevalence of Complications Among Patients with Diabetes 27
Table 2.10: Novel Risk Factors and Possible Mechanisms of the Excess Risk of
Coronary Heart Disease in Type 2 Diabetes Mellitus 28
Table 2.11: Major Causes of End-Stage Renal Disease 28
Table 2.12: Clinical Recommendations for Adults with Diabetes 29
Table 2.13: Laboratory Assessment of Diabetic Vascular Disease 29
Table 2.14: Average Years Gained Free of Diabetes-rela
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