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Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist
Date:11/27/2008

markets (U.S. and Europe). Helsinn Healthcare's products are eventually out-licensed to its worldwide consolidated network of partners for distribution. Helsinn Healthcare's key products in the US are Aloxi(R) (palonosetron), distributed by Eisai Inc., USA, and Gelclair(R). The active pharmaceutical ingredients and the drug products are manufactured at Helsinn Healthcare's cGMP facilities and supplied worldwide to its customers. Helsinn Healthcare's chemical business focuses on the pharmaceutical chemical process development and manufacturing of advanced intermediates, Active Pharmaceutical Ingredients (APIs) and High Potency Active Ingredients (HPAIs) for both the Helsinn group and its outsourcing partners.

For more information about Helsinn Healthcare, please visit http://www.helsinn.com

About Zealand Pharma

Zealand Pharma is a biopharmaceutical company dedicated to the discovery and development of innovative peptide-based drugs. Zealand Pharma is one of the leaders within the peptide area, a growing market with significant drug development activities including treatment of metabolic and cardiovascular diseases. All of Zealand Pharma's products target diseases and symptoms of significant unmet clinical need and commercial potential.

Since 1999, Zealand Pharma's scientists have built a pipeline that includes five compounds in clinical development, three of which have been out licensed to major pharmaceutical companies (Sanofi-Aventis, Wyeth and Helsinn Healthcare). All Zealand Pharma's compounds emerge from Zealand Pharma's own drug discovery.

AVE0010/ZP10, a pharmaceutical agent for the treatment of Type 2 Diabetes, has been out-licensed to Sanofi-Aventis, which is the world's third largest pharmaceutical corporation with a strong diabetes franchise. Phase III clinical trials were initiated in May 2008.

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SOURCE Helsinn Healthcare SA
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