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Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist
Date:11/27/2008

ith Zealand Pharma, which represents another important step in broadening and strengthening Helsinn Healthcare's pipeline of cancer supportive care products. We are confident that ZP1846 will be an important contribution to the treatment of chemotherapy-induced diarrhea, currently an unmet medical need and consequently, a positive impact on patients' quality of life. We believe that Helsinn's constant investment in R&D and in life-cycle activities of new and current products in this therapeutic area will allow us to fulfill our commitment to deliver benefits to the medical community and to alleviate the suffering of patients worldwide," commented Dr. Riccardo Braglia, Helsinn Healthcare's Chief Executive Officer.

"Diarrhea is a debilitating and potentially life-threatening side-effect of chemotherapy. Despite its high incidence and severity it is often under recognized and poorly managed: current available treatments are only palliative. CID remains therefore a huge unmet medical need. ZP1846 has a tremendous therapeutic potential by virtue of its unique mechanism of gut growth stimulation and reduction of gut atrophy and weight loss induced by the mucosal toxicity of chemotherapy. This project gives us the extraordinary opportunity to develop an agent that could prevent and/or treat CID enabling the best possible cancer treatment and reducing patients' morbidity," commented Dr. Sergio Cantoreggi, Senior Director, Head of Helsinn Healthcare's R&D.

Mr. Mogens Vang Rasmussen, Executive Vice President, Chief Operating Officer and Chief Financial Officer of Zealand Pharma commented: "Being able to partner ZP1846 with Helsinn Healthcare once again demonstrates Zealand Pharma's ability to bring innovative peptide projects from idea to clinical development and partnering. This agreement is the third major agreement concluded within the 10 year period Zealand Pharma has been operating and these important deals hig
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SOURCE Helsinn Healthcare SA
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