Navigation Links
Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist
Date:11/27/2008

LUGANO, Switzerland, November 27 /PRNewswire/ -- Helsinn Healthcare's Top management today announced that it has signed a partnering agreement with Zealand Pharma, for the development and worldwide commercialization of ZP1846, a GLP-2 (glucagon-like peptide-2) receptor agonist which provides a novel way to treat chemotherapy-induced diarrhea (CID), a debilitating condition affecting patients undergoing cancer treatment with a range of chemotherapies.

Under the terms of the agreement, Helsinn Healthcare will receive a worldwide exclusive license to ZP1846 and will be responsible for all further development, regulatory approvals, manufacturing, marketing and sales of the compound either on its own or through its sub-licensees. In return Helsinn Healthcare will pay Zealand Pharma development milestones and sales milestones for an undisclosed amount. In addition, Zealand Pharma will receive royalties on future sales and Zealand Pharma retains the marketing rights to the Nordic countries. The total value of the non royalty portion of the partnership is valued at EUR 140 million.

Zealand Pharma has applied its knowledge of peptide optimization and its proprietary SIP(r) technology to develop ZP1846, one of a series of novel peptides that specifically enhance the growth and function of the lining of the intestine. ZP1846 has completed Phase I in humans in the US. Zealand Pharma's pre-clinical studies have demonstrated that ZP1846 is useful in the prevention and/or treatment of injuries to the intestinal epithelium caused by chemotherapy treatment, resulting in a reduction in the incidence of chemotherapy-induced diarrhea. Today, serious gastrointestinal side effects are observed in up to 50% of patients undergoing certain forms of chemotherapy, which in turn may require dose modification or cessation of cancer chemotherapy.

"We are excited about this promising development and commercial cooperation w
'/>"/>

SOURCE Helsinn Healthcare SA
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Hearing Scheduled in the Delaware Court of Chancery for August 27, 2007 to Establish the Valid Approval and Consummation of the Merger Between PharmAthene, Inc. and Healthcare Acquisition Corp.
2. Healthcare Technologies Calls for a Shareholders Meeting to Approve the Nexgen Biofuels Transaction
3. Healthcare Technologies Reports Loss for 2007 Second Quarter & Six Months Results
4. Proceedings to Affirm Merger Between PharmAthene and Healthcare Acquisition Corp Initiated in Delaware Chancery Court
5. InterCure and Omron Healthcare (UK) Ltd. Announce Marketing Collaboration for Hypertension Market in United Kingdom
6. Apria Healthcare Chooses Masimo SET Pulse Oximetry for Use in the Companys Home Health Care Business
7. NuVasive to Present at Thomas Weisel Partners Healthcare Conference
8. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2007
9. Boston Scientific to Participate in the Bear Stearns 20th Annual Healthcare Conference
10. ADVENTRX Pharmaceuticals to Present at the 2007 Thomas Weisel Partners Healthcare Conference
11. Caliper Life Sciences Presentation at Thomas Weisel Partners Healthcare Conference to be Webcast

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2009)...URHAM, N.C., Nov. 27 Cromoz Inc., ...ater-soluble carbon nanotube-based cancer drug del...e carbon nanotubes, which have functional groups o...r drugs, was developed in partnership with the Ind...on nanotubes serves as a drug delivery vehicle wit...
(Date:11/25/2009)...URHAM, N.C., Nov. 25 Research Tria...rgy-efficient, single-treatment water purification...es to Andhra Pradesh, Minister of Rural Water Supp...derabad, India today. Initial tests, performed at ...rmed that the majority of the drinking water avail...
(Date:11/25/2009)..., ON, Nov. 25 /PRNewswire/ - Cytochroma today anno...oard of Directors. Dr. Moldt will replace Mr. Ulri...any,s Board. The number of Board members remains u...d to welcome Peter Moldt to the board and look for...e as Cytochroma continues to make progress in beco...
(Date:11/24/2009)...available in German . , Whether it,s CD pac...ags (Radio Frequency Identification) are increasin...e it possible to label objects or goods and identi...opriate scanner can read and process the data cont... goods under production conditions of up to 100 de...
Breaking Biology Technology:North Carolina Based Cromoz Inc. Launches Carbon Nanotechnology for Target Drug Delivery System in Cancer Treatment in Hyderabad, India 2North Carolina-based Cnanoz Unveils NanoPure(TM) to Government Leaders in Hyderabad, India 2Cytochroma Announces Appointment of Peter Moldt to Board of Directors 2Intelligence inside metal components 2
...lif., Dec. 10 DaVita Inc., a,leading provider of ...nic,kidney failure and disease (CKD), continues to...e during the month of December to complement the,e... (Logo: http://www.newscom.com/cgi-bin/prnh/2...a Week kicks off this week and is designed to rais...
...ts Show 2008 Revenue Growth Of 23% , , TORONT...ase today, Microbix announced results for the fisc...s profitable core business are continuing to fund ...peline opportunities which are expected to build s...ding to William J. Gastle, CEO of the Company. , ...
... New ProVue Model from Aven Delivers P... Ann Arbor, MI (PRWEB) December 10, 2008 --...vailable for added precision, flexibility and comf...ction applications. , ,The ProVue LED Magnifying L...bor, Mich., uses a ring of 60 lights and a 3-diopt...
Other Biology Technology:DaVita Launches 'Flu Fighter Program' in Support of National Influenza Week 2Microbix Uses Core Business Cashflow To Fund Late-Stage Pipeline To Build Shareholder Value In 2009 2Microbix Uses Core Business Cashflow To Fund Late-Stage Pipeline To Build Shareholder Value In 2009 3Microbix Uses Core Business Cashflow To Fund Late-Stage Pipeline To Build Shareholder Value In 2009 460 LED Lights Enhance Magnifying Lamp for Assembly, Engineering, Inspection or Research 260 LED Lights Enhance Magnifying Lamp for Assembly, Engineering, Inspection or Research 3
(Date:11/24/2009)...eld secrets of the earth,s history locked in its i... little information on the environments that have ...ears. Now, a team of researchers from nine institu... of $10 million dollars by the National Science Fo...literally. These scientists will drill through the...
(Date:11/24/2009)...sh . , The presence of increased body fat, a...ces in the blood, hinders the loss and maintenance... the University of Navarra conducted by Estbaliz G...acy. , The project, entitled "A nutrigenetic and...body weight and inflammation," examines how the in...
(Date:11/23/2009)...009 Applied mathematicians dissected the morpholo...aracteristic long leaf with a saddle-like arc mids... The simple cause of the lily,s fan-like shapeelas...rential growthwas revealed by using an equally sim...Liang, a postdoctoral student at Harvard,s School ...
Breaking Biology News(10 mins):LSU gets to the bottom of things -- in Antarctica 2It can be predicted the reaction obese patients will have to a diet 2The cause behind the characteristic shape of a long leaf revealed 2CONCERTA 28R 29 28methylphenidate HCl 29 LAUNCHES MOBILE WEB EXPERIENCE TO PROVIDE TOOLS AND SUPPORT FOR ADHD AWARENESS 56614 1CONCERTA 28R 29 28methylphenidate HCl 29 LAUNCHES MOBILE WEB EXPERIENCE TO PROVIDE TOOLS AND SUPPORT FOR ADHD AWARENESS 56614 2CONCERTA 28R 29 28methylphenidate HCl 29 LAUNCHES MOBILE WEB EXPERIENCE TO PROVIDE TOOLS AND SUPPORT FOR ADHD AWARENESS 56614 3CONCERTA 28R 29 28methylphenidate HCl 29 LAUNCHES MOBILE WEB EXPERIENCE TO PROVIDE TOOLS AND SUPPORT FOR ADHD AWARENESS 56614 4CONCERTA 28R 29 28methylphenidate HCl 29 LAUNCHES MOBILE WEB EXPERIENCE TO PROVIDE TOOLS AND SUPPORT FOR ADHD AWARENESS 56614 5U of I scientist 3A Public policy should promote family mealtimes 9845 1U of I scientist 3A Public policy should promote family mealtimes 9845 2U of I scientist 3A Public policy should promote family mealtimes 9845 3Michigan Tech scientists identify genes linked to Lou Gehrigs disease 9843 1Michigan Tech scientists identify genes linked to Lou Gehrigs disease 9843 2Michigan Tech scientists identify genes linked to Lou Gehrigs disease 9843 3
...apore (April 28, 2008) Obesity and corresponding...n. Weight and eating disorders have become especia...d for more information about how to deal with pedi...GE, the worlds fifth largest publisher of journals...hild, & Adolescent Nutrition, a multidisciplinary ...
...seem inextricably linked. However, new research pu...bon Balance and Management suggests that this may ... before we reach this saturation point. , The lan... than the atmosphere, and exchange carbon dioxide ...bsorbed by the land or the oceans vary in response...
...n be just as important as the genome itself, incre...netics focuses on the multiple influences on DNA a...nes are turned on or off during development and di...ed by Albert Jeltsch at Jacobs University, Breman,...n, and Xiaodong Cheng at Emory University, has now...
Other Biology News:Epigenetic research uncovers new targets for modification enzymes 2
Mouse Anti-SERCA 1 ATPase Monoclonal Antibody, Unconjugated, Clone IIH11 from Novus Biologicals
Vitality pIRES-hrGFP-1 Vector from Stratagene
Rabbit Serum from BioVision
...The Zero Background Cloning Kit includes the pZErO...E. coli. The pZErO-1 vector utilizes positive sele... of the Zeocin resistance gene reduces the overall...tion efficiencies. The kit contains all of the rea...
Biology Products: