Navigation Links
Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist
Date:11/27/2008

LUGANO, Switzerland, November 27 /PRNewswire/ -- Helsinn Healthcare's Top management today announced that it has signed a partnering agreement with Zealand Pharma, for the development and worldwide commercialization of ZP1846, a GLP-2 (glucagon-like peptide-2) receptor agonist which provides a novel way to treat chemotherapy-induced diarrhea (CID), a debilitating condition affecting patients undergoing cancer treatment with a range of chemotherapies.

Under the terms of the agreement, Helsinn Healthcare will receive a worldwide exclusive license to ZP1846 and will be responsible for all further development, regulatory approvals, manufacturing, marketing and sales of the compound either on its own or through its sub-licensees. In return Helsinn Healthcare will pay Zealand Pharma development milestones and sales milestones for an undisclosed amount. In addition, Zealand Pharma will receive royalties on future sales and Zealand Pharma retains the marketing rights to the Nordic countries. The total value of the non royalty portion of the partnership is valued at EUR 140 million.

Zealand Pharma has applied its knowledge of peptide optimization and its proprietary SIP(r) technology to develop ZP1846, one of a series of novel peptides that specifically enhance the growth and function of the lining of the intestine. ZP1846 has completed Phase I in humans in the US. Zealand Pharma's pre-clinical studies have demonstrated that ZP1846 is useful in the prevention and/or treatment of injuries to the intestinal epithelium caused by chemotherapy treatment, resulting in a reduction in the incidence of chemotherapy-induced diarrhea. Today, serious gastrointestinal side effects are observed in up to 50% of patients undergoing certain forms of chemotherapy, which in turn may require dose modification or cessation of cancer chemotherapy.

"We are excited about this promising development and commercial cooperation w
'/>"/>

SOURCE Helsinn Healthcare SA
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Hearing Scheduled in the Delaware Court of Chancery for August 27, 2007 to Establish the Valid Approval and Consummation of the Merger Between PharmAthene, Inc. and Healthcare Acquisition Corp.
2. Healthcare Technologies Calls for a Shareholders Meeting to Approve the Nexgen Biofuels Transaction
3. Healthcare Technologies Reports Loss for 2007 Second Quarter & Six Months Results
4. Proceedings to Affirm Merger Between PharmAthene and Healthcare Acquisition Corp Initiated in Delaware Chancery Court
5. InterCure and Omron Healthcare (UK) Ltd. Announce Marketing Collaboration for Hypertension Market in United Kingdom
6. Apria Healthcare Chooses Masimo SET Pulse Oximetry for Use in the Companys Home Health Care Business
7. NuVasive to Present at Thomas Weisel Partners Healthcare Conference
8. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2007
9. Boston Scientific to Participate in the Bear Stearns 20th Annual Healthcare Conference
10. ADVENTRX Pharmaceuticals to Present at the 2007 Thomas Weisel Partners Healthcare Conference
11. Caliper Life Sciences Presentation at Thomas Weisel Partners Healthcare Conference to be Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... 2014 Gain recognition for leadership ... of the biotech industry. Nominations are now being ... to you by the Bio Supply Management ... chain management professionals for the past 7 years. ... the Biotech industry – Manufacturers, Service Providers, Material ...
(Date:7/24/2014)... , July 24, 2014  Asterias Biotherapeutics, Inc. ... emerging field of regenerative medicine, announced today that ... presentation to investors on Tuesday, July 29, 2014, ... presentation will include an overview of Asterias, business ... webcast, visit http://www.ustream.tv/channel/asterias-biotherapeutics at least 15 ...
(Date:7/24/2014)... trained personnel, and detection dogs to safeguard airports ... revolutionary new electronic chip with nano-sized chemical sensors ... , The groundbreaking nanotechnology-inspired sensor, devised by Prof. ... of Chemistry and Center for Nanoscience and Nanotechnology, ... up the scent of explosives molecules better than ...
(Date:7/24/2014)... scientists are making progress in devising suitable means ... relies on quantum dotsa kind of artificial atom, ... new study demonstrates that changing the coupling of ... impulses can help better control them. This has ... quantum information units, which would produce faster quantum ...
Breaking Biology Technology:Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4Nano-sized chip 'sniffs out' explosives far better than trained dogs 2
... Yang, Associate Professor of Mechanical Engineering and Director of ... Technology, The Innovation University (TM), will receive funding from ... a Nanoimprint Lithography System (NIL) for the purpose of ... Stevens. The Co-PIs of the project are Drs. Besser, ...
... Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX) ... the safety and efficacy of Caldolor® ( ibuprofen ) ... ill adults. Published in the peer-reviewed journal Critical ... significantly more effective at reducing fever in hospitalized patients ...
... Castle Access, Inc. announces the appointment of ... the Castle Access organization with that of its ... provider, and gives clients in Southwestern US and ... data center and mission-critical managed services. ...
Cached Biology Technology:Nanoimprint lithography NSF grant awarded to micro device lab at Stevens 2Nanoimprint lithography NSF grant awarded to micro device lab at Stevens 3Newly Published Caldolor® Clinical Data Demonstrates 77% Reduction in Fever in Hospitalized Patients 2Newly Published Caldolor® Clinical Data Demonstrates 77% Reduction in Fever in Hospitalized Patients 3Newly Published Caldolor® Clinical Data Demonstrates 77% Reduction in Fever in Hospitalized Patients 4Castle Access Names New Managing Director 2Castle Access Names New Managing Director 3
(Date:7/25/2014)... A study published online in the International ... novel approach to preventing cervical cancer based on findings ... after removal of a discrete population of cells in ... study that looked at squamocolumnar junction cells, or SCJ ... have been implicated as the origins of cervical cancer. ...
(Date:7/25/2014)... of Adelaide has opened the way for the development of ... In Australia, annual barley production is second only to wheat ... of the most important diseases of barley. , Senior Research ... of special growths on the cell walls of barley plants ... , The research, by the ARC Centre of Excellence in ...
(Date:7/25/2014)... that the age girls reach puberty is influenced by ,imprinted ... parent contributes the gene. This is the first evidence ... birth and details of this study were published today in ... period, known as menarche, is a marker for the timing ... onset of menses varies between girls, is an inherited trait, ...
Breaking Biology News(10 mins):Clearing cells to prevent cervical cancer 2New hope for powdery mildew resistant barley 2Could age of first period influence development of diseases in older women? 2
... reveals critical molecular events in the origin of fat ... such as obesity and diabetes, as fat cells produce ... The study finds that a hormonal cocktail routinely used ... the transition from fat-cell precursors to full-blown fat, researchers ...
... study reveals critical molecular events in the origin of ... diseases, such as obesity and diabetes, as fat cells ... , The study finds that a hormonal cocktail routinely ... in the transition from fat-cell precursors to full-blown fat, ...
... how a common fish found along the West Coast can ... The study marks the first time that scientists have found ... vertebrate's brain that controls the vocal muscle system and the ... that understanding the auditory system of the plainfin midshipman fish ...
Cached Biology News:Key To Stem Cell Transplant Success Is Tricking Immune System 2Short-term Bio Sensors Monitor From Afar 2How fish hear and make sounds at same time 2
... , CapSure HS and CapSure Macro LCM ... of populations of pure cells from tissue ... Microdissection., Ensure the Integrity of Microdissected ... CapSure LCM Caps have a patented transfer ...
... MyiQ real-time PCR detection system offers an ... green fluorescent dyes such as FAM and ... with the iCycler thermal cycler, offering superior ... driven performance. The MyiQ real-time PCR detection ...
Opticon continuous fluorescence detector; includes optical base, analysis software, computer and monitor (this is an accessory for the DNA Engine thermal cyclers which must be ordered seperately)...
... are highly sensitive laser confocal systems designed ... advanced scanners that meet your expectations, differentiating ... and optimizing the signal on the bottom ... the range for increased sensitivity. Results with ...
Biology Products: