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Helix BioPharma reports Q2 2008 highlights, financial results
Date:3/10/2008

ix month periods ended January 31, 2008, compared to $310,000 and $600,000, respectively, for the same periods last year. Margins, on percentage basis, have remained relatively stable in both the three and six month periods ended January 31, 2008, when compared to 2007.

Research & development

Research & development costs for the three and six month periods ended January 31, 2008, totaled $1,029,000 and $1,811,000, respectively, compared to $1,065,000 and $1,973,000, respectively, a year ago. In the three and six month periods ended January 31, 2008, research & development expenditures for both L-DOS47 and Topical Interferon Alpha2-b were less than in the same periods a year ago, with the majority of the lower research and development expenditures related to L-DOS47.

The reduction in research and development expenditures for L-DOS47 in the period were related to the various stages of completion associated with the multiple projects within the L-DOS47 program. Helix intends to seek approval in 2008 from the U.S. Food and Drug Administration ("FDA") for a Phase I clinical study in lung adenocarcinoma patients and, therefore, is currently advancing its L-DOS47 scale-up manufacturing program in anticipation of furnishing product for the clinical trial.

Research and development expenditures related to the Phase II trial in Sweden for ano-genital warts ("AGW") were more than offset by the reduction in costs associated with the Phase II study in Germany for women with precancerous, HPV induced low-grade cervical lesions.

The late-stage Phase II study in Germany was completed during the six month period ended January 31, 2007. Based on the positive findings, the Company is currently developing plans for a large, randomized, placebo-controlled double-blind study to evaluate the product in an expanded patient population in addition to preparatory work in anticipation of Investigational New Drug ("IND") and Clinical Trial Application ("CTA") f
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SOURCE Helix BioPharma Corp.
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