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Helix BioPharma Form 20-F Registration Statement Declared Effective by SEC
Date:3/12/2009

field of cancer therapy. The Company is actively developing innovative products for the prevention and treatment of cancer based on its proprietary technologies. Helix's product development initiatives include its Topical Interferon Alpha-2b and its novel L-DOS47 new drug candidate. Helix is listed on the TSX under the symbol "HBP".

For further information contact:

    Investor & Media Relations
    Ian Stone                         Robert Flamm, Ph.D.
    Russo Partners LLC                Russo Partners LLC
    Tel:  (619) 528-2220              Tel: (212) 845-4226
    Fax:  (619) 528-2297              Email: robert.flamm@russopartnersllc.com
    Email: ian.stone@russopartnersllc.com    www.russopartnersllc.com

The Toronto and Frankfurt Stock Exchanges have not reviewed and do not accept responsibility for the adequacy or accuracy of the content of this News Release. This News Release contains certain forward-looking statements and information regarding the registration of Helix's common shares with the U.S. Securities & Exchange Commission and Helix's business, which statements and information can be identified by the use of forward-looking terminology such as "believe," "look," "next", "will," "future", "anticipation", "plan", "developing", or variations thereon, or comparable terminology referring to future events or results. Forward looking statements and information are statements and information about the future and are inherently uncertain. Helix's actual results could differ materially from those anticipated in these forward-looking statements and information as a result of numerous risks and uncertainties including without limitation: uncertainty whether Helix's shares will be actively solicited and traded by licensed brokers in the U.S. or that Helix's liquidity and U.S. investor ba
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