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Helix BioPharma Announces $11.4 Million Private Placement
Date:9/30/2008

AURORA, Ontario, Sept. 30 /PRNewswire/ -- Helix BioPharma Corp. (TSX, FSE: "HBP") today announced that it has received subscriptions for the purchase, by way of private placement, of a total of 6,800,000 units at $1.68 per unit, for gross proceeds totaling CDN$11,424,000. The Company anticipates closing the private placement within the next ten days.

Each unit consists of one common share and one-half of one common share purchase warrant, with each whole common share purchase warrant entitling the holder to purchase one common share at a price of $2.36 for up to three years after the closing date of the private placement.

"This is an exciting time for Helix as we open clinical trial sites in Germany for our trial of Topical Interferon Alpha-2b for the treatment of ano-genital warts, prepare for additional clinical trials for this treatment and continue to progress towards clinical testing with L-DOS47," said John Docherty, president of Helix BioPharma. "We plan to use the proceeds from the placement for working capital, primarily to support these research and development initiatives."

About Helix BioPharma Corp.

Helix BioPharma Corp. is a biopharmaceutical company specializing in the field of cancer therapy. The Company is actively developing innovative products for the prevention and treatment of cancer based on its proprietary technologies. Helix's product development initiatives include its Topical Interferon Alpha- 2b and its novel L-DOS47 new drug candidate. Helix is listed on the TSX under the symbol "HBP".

For further information contact:

Investor & Media Relations

Ian Stone

Russo Partners LLC

Tel: (619) 814-3510

Fax: (619) 955-5318

Email: ian.stone@russopartnersllc.com

David Schull

Russo Partners LLC

Tel: (212) 845-4271

Email: david.schull@russopartnersllc.com

http://www.russopartnersllc.com

The Toronto and Frankfurt Stock Exchanges have not reviewed and do not accept responsibility for the adequacy or accuracy of the content of this News Release. This News Release contains forward-looking statements and information regarding a proposed private placement and the Company's activities, which statements and information can be identified by the words "anticipates, "next", "prepare", "towards", "plan", "developing", and similar future-oriented expressions. Actual results or events could differ materially from these forward-looking statements and information due to numerous factors, including without limitation, the risk that the proposed placement may not close as anticipated or at all; that proceeds of the placement may be used for purposes other than those currently anticipated; research & development risks and uncertainty whether the Company's drug candidates will undergo further trials or clinical testing or will otherwise be developed at all; and Helix's need for additional future capital. These and other risks and uncertainties are further discussed in Helix's latest Annual Information Form at http://www.sedar.com. Forward-looking statements and information are based on the assumptions and expectations of Helix's management at the time they are made, and Helix does not assume any obligation, except as required by law, to update any forward-looking statement or information should those assumptions or expectations, or other circumstances change.


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SOURCE Helix BioPharma Corp.
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