Navigation Links
Heart disease: Research off the beating patch

TUCSON, ARIZ. It is an amazing sight: What looks like a tiny beating heart is actually a piece of synthetic, gauze-like mesh, barely the size of a fingernail, floating in a Petri dish. And yet it keeps squeezing away, nice and rhythmically.

Researchers at The University of Arizona's Sarver Heart Center and the Southern Arizona Veterans Administration Health Care System (SAVAHCS) have come a step closer to repairing hearts damaged by a heart attack or weakened by chronic heart failure.

"We have developed a delivery system that allows us to introduce living, healthy heart muscle cells into damaged areas of the heart in a way that is much more efficient than the conventionally practiced method of injecting cells into heart tissue," says study leader Steven Goldman, MD.

Unlike most existing approaches, in which cardiac cells with no supporting structure are injected into heart tissue, Goldman's group uses a patch (Theregen Inc. San Francisco) made from microscopically thin fibers that serve as a scaffold to which the cells can adhere.

The group's latest achievements have attracted the attention of the American Heart Association, who picked the research as one of the most noteworthy achievements of this year's Cardiovascular Sciences Annual Conference in Las Vegas, Nev.

"Ultimately, we hope to use our system in patients with chronic heart failure and, possibly, to prevent heart failure in patients who had a heart attack," says Jordan Lancaster, BS, a pre-doctoral fellow in Dr. Goldman's lab who will present the research at the meeting on July 21, 2009.

Dr. Goldman and his team discovered that when they "seed" a vicryl mesh patch with a sufficiently large number of heart muscle cells (2.5 million or more), the cells start behaving just like their counterparts in the real organ: They contract synchronously at about 70 beats per minute even without any outside stimulation.

"Our work shows that we can pu

Contact: Ann Cisneros
University of Arizona Health Sciences Center

Page: 1 2

Related biology technology :

1. Thoratec Announces HeartMate II(R) PMA Will be Reviewed by FDA Advisory Panel
2. ATS Medical Expands Open Pivot Heart Valve Offerings
3. Cardicas C-Port(R) Flex A Anastomosis System Allows Surgeons to Perform Revolutionary Closed-Chest Heart Bypass Surgeries
4. Signalifes Dr. Harmison Launches Award-Winning Ambulatory Heart Monitor
5. Cleveland Clinic-Led Research Uncovers New Mechanism That Heightens Risk of Heart Disease
6. New Licence for Cubicin(R) (daptomycin), the First in a Novel Class of Antibiotic, is Announced Today for the Treatment of Serious Bloodstream and Heart Infections Caused by the Most Problematic UK Organisms, Including MRSA
7. Panel to Discuss the Far-Ranging Effects and Consequences of Heart Disease, Which is the Leading Killer in Both Men and Women in the United States
8. Cheetah Medicals NICOM Non-Invasive Cardiac Output Monitor Featured in a Presentation at the Heart Failure Society of America (HFSA) Annual Meeting
9. New Study Shows Promise for Hydrogen Sulfide in Reducing Heart-Attack Damage, Ikaria Announces
10. Americas Heartland Launches Third Season Highlighting Contributions of American Farmers and Ranchers
11. CV Therapeutics Announces Presentations at American Heart Association Scientific Sessions 2007
Post Your Comments:
Related Image:
Heart disease: Research off the beating patch
(Date:10/9/2015)... , Oct. 9, 2015 Governor ... clinical stage biopharmaceutical company focused on developing T-cell receptor ... high-paying jobs with a new expansion project. ... news for the commonwealth as 110 new, high-paying jobs ... Tom Wolf . "My budget proposal includes sustained funding ...
(Date:10/9/2015)... ... , ... Leading microbial genomics startup uBiome today launched the first-ever microbiome app, ... management and the microbiome. The study uses the ResearchKit framework, designed by Apple, to ... The uBiome app is available as a free download from the App Store. The ...
(Date:10/8/2015)... 8, 2015  ATCC, the premier global biological materials ... been selected by The Michael J. Fox Foundation for ... academic, pharmaceutical, and biotechnology organizations committed to speed a ... United States , and more than 5 million ... United States , and more than 5 million ...
(Date:10/8/2015)... Oct. 8, 2015 The 2015 Nobel Prize in ... of Texas at Dallas. Aziz Sancar , who earned ... Dallas in 1977, is one of three scientists who ... monitor and repair damaged DNA on a molecular level.  --> ... cell biology from UT Dallas in 1977, ...
Breaking Biology Technology:
... Preventative Testing , , CINCINNATI, June 23 ... nation,s leading provider of physician office-based patient-education programs, reports ... programs, 16.9 percent more patients had PSA tests (prostate ... (colon cancer screening) compared to patients in practices without ...
... ... MasterControl Inc., a global provider of GxP process and document ... world leading provider of high performance electronic regulatory submission solutions for ... the Drug Information Association (DIA) 45th Annual Meeting. GxP2eCTD is ...
... June 23 SyntheMed, Inc. (OTC Bulletin Board: SYMD), ... of anti-adhesion products, announced today that the company was ... Innovation Award in pediatrics. The company is ... Sullivan medical device analysts in recognition of the development ...
Cached Biology Technology:
(Date:9/10/2015)... 2015 Report Details Emerging ... Opportunities and Revenue Prospects to Help You Stay ... especially new drug classes? Get the latest technological ... exclusive market data and industry knowledge, benefitting your ... opportunities and sales predictions. Visiongain,s new study ...
(Date:9/8/2015)... --  TREW Marketing and today ... for Engineers TM : Content and Online Marketing . ... about engineers, preferences for online content marketing and channels ... and trust, and where they look for that content ... with how to best implement online and content marketing ...
(Date:9/1/2015)... MOUNTAIN VIEW, Calif. , Sept. 1, 2015 ... interaction with travelers during airport passenger screening. This ... which the passenger screening process will become unintrusive. ... and pre-clearance based on voluntary background investigations will ... analysis from Frost & Sullivan, Global Airport ...
Breaking Biology News(10 mins):
... MEDFORD/SOMERVILLE, Mass. Maria Flytzani-Stephanopoulos of Tufts University,s ... AAAS Fellow for distinguished contributions to the field ... reactions on nanoscale metal oxides in fuel conversion ... is an honor bestowed upon AAS members by ...
... Eight Arizona State University faculty members are among ... for the Advancement of Science (AAAS), a prestigious international ... society. Brad Allenby, Richard Creath, James Elser, Patricia ... Spence will be recognized Feb. 14 at the Fellows ...
... experiment, researchers have provided some clues to one of ... together to form the basis of life. ... JBC , demonstrated how ancient RNA joined together to ... precursor to DNA, normally expands one nucleic base at ...
Cached Biology News:
supplied with 10x reaction buffer...
... Klenow fragment is a ... coli DNA Polymerase I ... -> 5 exonuclease activity, but ... activity. Klenow retains the polymerization ...
Mouse monoclonal [HL-37] to HLA DQ1 + HLA DQ3 ( Abpromise for all tested applications)....
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
Biology Products: