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HABIT Study Highlights Home BNP Testing May Allow for Earlier Interventions and Better Management of Heart Failure Patient
Date:10/4/2011

r to support this conclusion.  "The routine availability of BNP values in established heart failure patients could provide us with the first direct and objective indicator of the heart's response to change in a patient's condition," stated Maisel.  "BNP could become an important monitoring tool for use in the homes of patients to manage the disease remotely, thereby identifying decompensation earlier to reduce healthcare costs and downstream re-hospitalizations."

While the results of HABIT suggest that remote BNP monitoring could lead to significant improvements in how heart failure patients are managed, more data is needed to understand the extent to which healthcare providers can intervene with patients and reduce hospitalizations, lower healthcare costs, and enhance quality of life.  A further study to investigate these matters as part of the next phase of the trials will be conducted in the US.  

This multi-center, interventional trial will be designed to analyze the ability of BNP to improve upon today's tools for managing heart failure and prevent re-hospitalization.  In particular, the study will compare today's standard of care, which involves monitoring symptoms of heart failure and body weight changes following hospital discharge under the management of hospital-based outpatient heart failure clinics, to an algorithm that incorporates routine, home BNP measurements and will assess the extent to which this reduces hospital re-admissions and improves patient outcomes.  The study is expected to commence in 2012.  Alere has also undertaken a multinational study in Europe and Asia to further investigate the utility of home BNP testing coupled with clinical interventions and identify the value of this approach to decreasing HF related events.  This study is currently underway and results are expected to be released in 2013.

"The potential value of natriuretic peptide guided heart failure management is
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SOURCE Alere Inc.
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