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Global High Throughput Screening (HTS) Industry
Date:9/8/2011

Way 18

High Throughput Improves R&D Efficiency 19

High Throughput Screening (HTS) 19

The Equipment 19

The Process 20

HTS Robotics Supports Miniaturization 21

HTS and uHTS 21

Functional and Non-Functional - Two Types of High Throughput

Assays 21

Setting up HTS Facilities - An Expensive Affair 21

Important Components of HTS 22

Few popular Chemical Libraries Used in Chemical Biology and

Drug Discovery 22

Table 4: Screening Throughput of Plates (includes

corresponding Graph/Chart) 22

Distinctions Between Bench Top and HTS Assays 23

6. HTS AND THE PHARMA INDUSTRY 24

Impact of HTS on the Pharmaceutical Industry 24

The Underlying Technology and Market Factors 24

High Costs Involved with Sophistication - A Matter of Concern 24

The HTS Business in Pharma Industry 25

What Lies Ahead for HTS 25

Hit and Lead Generation Strategies 26

Different Stages in Hit and Lead Generation 26

From 'Hit' to 'Lead' in HTS - A Complex Endeavor 26

7. DRUG DISCOVERY - AN OVERVIEW 28

Drug Discovery - Definition 28

Drug Discovery Process 28

Drug Discovery Technologies 28

8. COMPUTER AIDED DRUG DISCOVERY (CADD) 30

The Evolution of Computer Aided Drug Discovery (CADD) Processes 30

CADD 30

High Throughput Screening 30

Virtual Screening 31

Cloud Computing 31

9. PRODUCT INNOVATIONS/INTRODUCTIONS 32

Tox21 Launches Novel Robotic High Speed Screening System 32

Life Technologies Introduces TaqMan OpenArray MicroRNA Panels 32

Zyleris Introduces Screening Service for Drug Development 32

Genosphere Introduces PepLib™ Custom Peptide Library Synthesis 33

PerkinElmer Launches Lance Ultra cAMP Detection Kit for

Profiling GPCRs 33

PerkinElmer Introduces Epigenetics Detection Reagents for HTS

of New Drug Candi
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