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Global Apoptosis Industry
Date:11/8/2011

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2. INDUSTRY OVERVIEW 4

Apoptosis: A Natural Part of Cell Lifecycle 4

The Cell Death Pathway: A Review 4

Apoptosis Modulating Drugs All Set for Commercial Stage

Competition 5

Table 1: Apoptosis Drugs Pipeline Scenario Worldwide (2008):

Percentage Share Breakdown of Number of Apoptosis Modulating

Drugs in Development by Development Stage (includes

corresponding Graph/Chart) 6

R&D Scenario 6

Table 2: Apoptosis R&D Scenario Worldwide (2010): Percentage

Share Breakdown of Number of Apoptosis Modulating Drugs in

Development by Treatment Area (includes corresponding

Graph/Chart) 7

Table 3: Apoptosis Drug Development Worldwide (2010):

Percentage Share Breakdown of Number of Apoptosis Modulating

Drugs in Development by Agent Type (includes corresponding

Graph/Chart) 7

Table 4: Top Nations for Apoptosis Research (2011):

Breakdown of Number of Researchers Involved in Apoptosis

Research by Country (includes corresponding Graph/Chart) 8

Popular Classes of Molecules Influencing the Apoptotic

Process: A Review 8

Noteworthy Molecular Targets for Apoptosis 8

Death Receptors 8

Caspases 9

IAPs and SMAC 9

Bcl-2 proteins 9

p53 9

Table 5: Apoptosis Drugs Pipeline Worldwide (2010):

Percentage Share Breakdown of Number of Apoptosis

Modulating Agents in Development by Molecular Target 9

HSP90: A Popular Gene Target for Apoptosis 10

Apoptosis: The Key to Cutting Edge Cancer Treatment/Therapies 10

Table 6: Apoptosis R&D in Cancer Treatment (2010):

Percentage Share Breakdown of Number of Apoptosis Modulating

Drugs in Development by Type of Cancer (includes

corresponding Graph/Chart) 11

Focus on Targeted Therapy Bodes Well for Apoptosis-Targeted

Therapies for Cancer 11

Overcoming Therapy/Drug Resistan
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