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Glencoe Software and The Journal of Cell Biology Pioneer Publishing of Genome-Wide Screens
Date:9/7/2011

SEATTLE, Sept. 7, 2011 /PRNewswire/ -- The Journal of Cell Biology (JCB), The Rockefeller University Press and Glencoe Software are pleased to announce their next enhancement to the JCB DataViewer, the world's first system for sharing and archiving published scientific image data. Starting today, data from genome-wide high-content screens (HCS) can be published online, directly associated with papers published in JCB. HCS data are increasingly used to determine the effects of systematic disruption of all genes that govern a specific cell biological process. The approach is valuable because it allows scientists to uncover new and unexpected factors involved in physiology and disease and thus helps identify new targets for drug therapy. While these screens are now widely used, venues for sharing the data generated by them and publishing those data in their entirety are limited. The JCB DataViewer now makes these very large datasets readily available via a standard browser interface and easily mined for information through interactive tools developed for this application.

First released in December 2008, the JCB DataViewer (http://jcb-dataviewer.rupress.org) has been under continuous development to support new data types and to provide new functionality for its users. This new version of the JCB DataViewer allows authors to archive and share HCS data and allows the scientific community to interactively browse and, for the first time, download original screen data to their own computers for more detailed analysis. Public distribution of these datasets creates opportunities for further discovery by scientists beyond those that performed the original experiments.

The JCB DataViewer currently contains original image data (multi-dimensional image data taken directly from a microscope imaging platform) associated with 195 manuscripts published in JCB, and the image data submission rate by authors is ste
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