Navigation Links
GlaxoSmithKline and Mpex Pharmaceuticals Form Alliance to Develop Novel Efflux Pump Inhibitors for Use Against Serious Gram-Negative Infections
Date:6/16/2008

option, Mpex will receive tiered royalties, which are dependent on sales achieved, for EPIs used in combination with commercially available antibiotics and with proprietary GSK antibiotics. GlaxoSmithKline will participate in the alliance through its Infectious Diseases Centre of Excellence for Drug Discovery (ID CEDD).

"We believe this collaboration has the potential to lead to a number of important new anti-infective products," said Daniel Burgess, President and CEO of Mpex Pharmaceuticals. "The critical role of antibiotic efflux has been well recognized in bacterial resistance, but to date, safe and effective efflux pump inhibitors have not been developed. Given the progress Mpex has made in this program over the last several years, we are optimistic that combining our efforts with an industry leader such as GlaxoSmithKline will maximize our chances of success to develop a portfolio of products from this platform technology that is greater than we could hope to develop on our own. In addition, GlaxoSmithKline has an impressive array of novel new classes of antibiotics in development, and we believe that a number of these antibiotic opportunities could benefit from the addition of an Mpex efflux pump inhibitor."

"Antibiotic discovery has faced tremendous challenges with the discovery of only two new classes of antibiotics over the last 3 decades," stated Zhi Hong, Senior Vice President of the ID CEDD at GlaxoSmithKline. "Novel discovery-enabling and paradigm-shifting approaches are needed to address the ever increasing medical needs due to life-threatening bacterial infections and drug resistance. Efflux pump inhibitors have the potential to add value to existing antibiotics and also enable progressive development of GSK's novel antibiotic pipeline. Mpex has a first rate entrepreneurial R&D team with deep experience in antibacterial research and has validated efflux pump inhibition for potentiation of antibacterial activity, as well as expanding the
'/>"/>

SOURCE Mpex Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. GlaxoSmithKline Signs Licensing Agreement With Compendia Bioscience
2. GlaxoSmithKline Named A Top Employer for Promoting Healthy Lifestyles
3. GlaxoSmithKline Commences Tender Offer to Acquire Sirtris Pharmaceuticals
4. GlaxoSmithKline to Acquire Sirtris Pharmaceuticals, a World Leader in Sirtuin Research and Development
5. Pharmacopeia to Receive $5 Million Payment from GlaxoSmithKline
6. Ingenuity Systems Extends Enterprise-Level Software Agreement With GlaxoSmithKline
7. Vaccinex Antibody Licensed to GlaxoSmithKline
8. GlaxoSmithKline Announces Data on TYKERB(R) (Lapatinib) Plus Capecitabine for the Treatment of HER2 Positive Breast Cancer Brain Metastases
9. GlaxoSmithKline Responds to JAMA Article on the ICES Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes
10. GlaxoSmithKline Consumer Healthcare Recommends Maintaining FDAS Current Two-Class Drug System
11. BioWa Announces Licensing of BioWas POTELLIGENT(R) Technology by GlaxoSmithkline for Use in Antibody Research and Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Sept. 17, 2014  The In Silico Drug Discovery ... be featured at the conference, which takes place at ... 3 and 4, 2014. Researchers, students, drug developers, business ... the following: KEYNOTE SPEAKERS ... Skaggs School of Pharmacy Drug Discovery with ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 A ... occurring microorganisms such as bacteria, fungi, and algae ... water, methane, biomass, inorganic compounds, carbon dioxide, and ... expanding customer base and improved costs, biodegradable polymers ... economically viable alternative to conventional polymers. Primary factors ...
(Date:9/17/2014)... Terracon Corporation has announced the introduction of ... This addition to the company’s industry-leading line of ... and available in 125 or 250 gallon capacities. ... weeks or less. , The new pre-engineered TerraPure tank ... existing TerraPure tank line – plus quick turnaround. ...
(Date:9/17/2014)... 2014 /PRNewswire/ - SQI Diagnostics Inc. (TSX-V: SQD) (OTCQX: ... proprietary technologies and products for advanced microarray diagnostics, today ... trading in the United States ... commence on September 17, 2014 on the OTCQX under ... on the TSX Venture Exchange under its existing symbol ...
Breaking Biology Technology:In Silico Drug Discovery Conference Announces Speakers and Topics 2In Silico Drug Discovery Conference Announces Speakers and Topics 3In Silico Drug Discovery Conference Announces Speakers and Topics 4In Silico Drug Discovery Conference Announces Speakers and Topics 5In Silico Drug Discovery Conference Announces Speakers and Topics 6In Silico Drug Discovery Conference Announces Speakers and Topics 7Growing Demand for Eco-Friendly Products Drives the Global Biodegradable Polymers Market, According to New Report by Global Industry Analysts, Inc. 2Growing Demand for Eco-Friendly Products Drives the Global Biodegradable Polymers Market, According to New Report by Global Industry Analysts, Inc. 3Terracon Introduces Pre-Engineered TerraPure® Tank for Ultrapure Water Applications 2SQI Diagnostics to begin Trading on the OTCQX Marketplace in the United States 2SQI Diagnostics to begin Trading on the OTCQX Marketplace in the United States 3
... Biotech and pharma,companies are increasingly relying on ... Engineering & Biotechnology News (GEN). The,technique can provide ... drug,candidates for toxic effects, according to an article ... )., "Better screening technologies, noninvasive monitoring, and ...
... /PRNewswire-FirstCall/ - Oncothyreon Inc.,(Nasdaq: ONTY ) (TSX:ONY) ... and preclinical studies of PX-866 were presented at ... Research (AACR) in,San Diego, held April 12-16, 2008. ... plans for these product candidates. Oncothyreon,is currently conducting ...
... Anavex Life,Sciences Corp. ("ANAVEX") (OTCBB: AVXL) today announced ... of Clinical Development as the,company prepares to enter ... the next 12 months., Dr. Goundis has ... of,clinical trials, including leadership positions at Speedel AG ...
Cached Biology Technology:Genetic Engineering & Biotechnology News Reports on Growing Use of Cell-Based Assays 2Data for Oncothyreon's PX-12 and PX-866 presented at AACR Annual Meeting 2Data for Oncothyreon's PX-12 and PX-866 presented at AACR Annual Meeting 3Data for Oncothyreon's PX-12 and PX-866 presented at AACR Annual Meeting 4Data for Oncothyreon's PX-12 and PX-866 presented at AACR Annual Meeting 5Anavex appoints Dr. Dimitri Goundis to lead Clinical Development 2Anavex appoints Dr. Dimitri Goundis to lead Clinical Development 3Anavex appoints Dr. Dimitri Goundis to lead Clinical Development 4
(Date:9/16/2014)... at the Columbia Center for Children,s Environmental Health at ... to demonstrate an association between childhood asthma and prenatal ... of household products. Results appear online in the journal ... to mothers exposed during pregnancy to higher levels of ... had a 72 percent and 78 percent increase in ...
(Date:9/16/2014)... Hopkins neuroscientists have discovered the "molecular brakes" that time ... cochleas of mice. These "hair cells" translate sound waves ... and are interpreted as sounds. If the arrangement of ... A summary of the research will be published in ... , "The proteins Hey1 and Hey2 act as brakes ...
(Date:9/16/2014)... EUGENE, Ore. -- Each tree species has its own ... researchers and colleagues from other institutions who studied the ... growing on a Panamanian island. , "This study demonstrates ... plant families and with different ecological strategies possess very ... Steven W. Kembel, a former postdoctoral researcher in the ...
Breaking Biology News(10 mins):Phthalates heighten risk for childhood asthma 2Phthalates heighten risk for childhood asthma 3Hey1 and Hey2 ensure inner ear 'hair cells' are made at the right time, in the right place 2Microbiome research shows each tree species has a unique bacterial identity 2
... be difficult for a terrorist to obtain genes from the ... Armed with a fake email address, a would-be bioterrorist could ... online, and receive them by post within weeks. , That's ... the bioterror risks posed by the booming business of gene ...
... students have discovered the antler of an Irish Elk in cliffs ... the exact age of the antler has yet to be determined, ... lived around 11,000 years ago. The giant deer roamed the open ... of the last Ice Age, as the glaciers retreated northwards. ...
... Medical Institute researchers have discovered that pheromones essential for ... and not by the vomeronasal system, as researchers had ... epithelium, which was presumed to be mostly involved with ... pheromone detection. , Howard Hughes Medical Institute investigator ...
Cached Biology News:The bioweapon is in the post 2The bioweapon is in the post 3The bioweapon is in the post 4Students discover 11,000 year old remains of Irish Elk 2Olfactory system detects pheromones that control reproduction 2Olfactory system detects pheromones that control reproduction 3Olfactory system detects pheromones that control reproduction 4
... patented technology, the Lone Wolf valve has ... Open proportional valve available on the market. ... repeatable high-speed performance, and ensures maximum accuracy., ... Enhances system control and patient comfort. , ...
... offers the same benefits as the VSO valve ... is critical or flow is required below 600 ... of gas in proportion to the input current., ... width modulation; closed loop feedback delivers optimal system ...
... from non-demolished blood that is ... The donors are not medicated ... maintained on an antibiotic free ... : 85 mg/ml (by Refractometry).Strain: ...
... 96-well Filter Plates are offered in several ... um depth filter plates are ideal to ... Filtration is simple, versatile, and necessary to ... Captiva 10 um glass fiber and 20 ...
Biology Products: