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GlaxoSmithKline Awarded U.S. Department of Defense Contract to Pursue Novel Antibacterial Research Program
Date:9/18/2007

ration. New treatments must not only be toxic to the pathogen, but must also overcome the barriers to entry into the cell.

"Through this innovative collaboration with DTRA, GSK will focus its experience and resource in drug discovery on new antibacterial solutions that address biothreat pathogens as well as conventional Gram negative infections acquired in the hospital," said Dr. David Payne, Group Director, Antibacterial Research, Infectious Diseases Center for Excellence in Drug Discovery (ID CEDD) at GSK.

With few new antibiotic classes being developed in the last 40 years and growing resistance of various types of bacteria to treatment, GSK is progressing a growing portfolio of antibiotic candidates. The ID CEDD, formed earlier this year, is exclusively dedicated to discovering and developing novel treatments for bacterial and other types of infections.

"GSK is committed to identifying and progressing novel antibacterials that address this rapidly emerging public health threat," said Dr. Patrick Vallance, Senior Vice President, GSK Drug Discovery. "This agreement with DTRA provides a substantial resource towards address the challenges of this area and will enable us to accelerate the delivery of new Gram negative antibacterials for patients."

In addition to this agreement, GSK previously announced further support for its Gram negative research program from the Wellcome Trust through their 91 million Seeding Drug Discovery initiative which aims to assist researchers and companies, small and large, to take forward early-stage drug discovery projects in small molecule therapeutics. It is intended that these projects will then be taken up for further research and development by industry.

About the Defense Threat Reduction Agency

The Defense Threat Reduction Agency (DTRA) is an agency within the U.S. Department of Defense dedicated to leveraging the latest scientific resources, expertise and capabilities to ensure the United States
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SOURCE GlaxoSmithKline
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