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GlaxoSmithKline Announces Data on TYKERB(R) (Lapatinib) Plus Capecitabine for the Treatment of HER2 Positive Breast Cancer Brain Metastases
Date:12/17/2007

any information, visit GlaxoSmithKline at http://www.gsk.com.

Cautionary statement regarding forward-looking statements

Under the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, the company cautions investors that any forward-looking statements or projections made by the company, including those made in this Announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Factors that may affect the Group's operations are described under 'Risk Factors' in the 'Business Review' in the company's Annual Report on Form 20-F for 2006.

Note to Editors

TYKERB(R) is a registered trademark of the GlaxoSmithKline group of companies in the United States.

TYVERB(R) is a registered trademark of the GlaxoSmithKline group of companies in Europe and is the proposed trade name in certain markets, pending regulatory approval.

Herceptin(R) is a registered trademark of Genentech, Inc. in the U.S. and Roche Pharmaceuticals in Europe.

Xeloda(R) is a registered trademark of Roche Pharmaceuticals.

To access the latest GSK Oncology media materials, visit http://www.gsk.com/media.

Enquiries:

US Media enquiries: Sarah Alspach +1 919 483 2839

Mary Anne Rhyne +1 919 483 2839

UK Media enquiries: Philip Thomson +44 20 8047 5502

Claire Brough +44 20 8047 5502

Joss Mathieson +44 20 8047 5502

Alice Hunt +44 20 8047 5502

European Analyst/Investor enquiries:

David Mawdsley +44 20 8047 5564

Sally Ferguson +44 20 8047 5543

US Analyst/ Investor enquiries:


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SOURCE GlaxoSmithKline
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