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GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI)
Date:3/7/2012

tory and clinical research into progress against the AIDS epidemic. Over 4,000 leading researchers and clinicians from around the world convene in a different location each year for the conference.

The first generation GeoVax vaccine that does not co-express GM-CSF has shown excellent safety and reproducible vaccine responses in Phase 1 and Phase 2a clinical trials in over 400 uninfected people. These trials, supported and conducted by the U.S. National Institutes of Health HIV Vaccine Trials Network, set the stage for the 2nd generation GM-CSF co-expressing vaccine to move from its initial Phase 1 safety testing (slated to start in March of this year) to a Phase 2b efficacy trial in participants who are at high risk of exposure to HIV. The vaccine is designed for the "clade B" version of the HIV virus prevalent in the Americas. Since 1989, the United States, despite education and availability of drugs, has consistently suffered about 55,000 new infections per year. And according to a 2010 study by the U.S. Centers for Disease Control (CDC), of those individuals in the United States who are diagnosed with HIV, only 35% ultimately achieve viral load suppression through drug treatment. Thus, there is an obvious need for therapies to complement drug treatment.

About GeoVax Labs, Inc.
GeoVax is a biotechnology company developing human vaccines for diseases caused by HIV. Our goals include developing HIV/AIDS vaccines for global markets, overseeing the manufacture and testing of these vaccines under GMP/GLP conditions (FDA guidelines), conducting clinical trials for vaccine safety and effectiveness, and obtaining regulatory approvals to move the product forward. GeoVax's vaccines are unique in expressing virus like particles that display the trimeric membrane bound form of the HIV-1 envelope glycoprotein. All preventative Phase 1 human clinical trials conducted to date tested various combinations and doses of our DNA and MVA vaccines, thei
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