Navigation Links
GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI)
Date:3/7/2012

ATLANTA, March 7, 2012 /PRNewswire/ -- Harriet L. Robinson, Ph.D., Chief Scientific Officer at GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), a biotech company specializing in the development of HIV/AIDS vaccines, announced the results of a study suggesting that scientists may be one step closer to a vaccine that protects against multiple exposures to HIV infections. The study results were unveiled by Dr. Robinson during a presentation in Seattle at the 2012 Conference on Retroviruses and Opportunistic Infections (CROI).

Dr. Robinson, working alongside Rama Rao Amara, Ph.D., Associate Professor of Microbiology and Immunology, Yerkes National Primate Research Center, and member of the Emory Vaccine Center, tested a novel vaccine against HIV/AIDS for the ability to protect non-human primates against a series of 36 exposures to simian immunodeficiency virus (SIV) given in three clusters of 12 each over more than 2.5 years. The serial exposures were initiated using the SIVE660 virus that is genetically distinct from the vaccine, followed by exposure to SIV251, the most potent strain of SIV used in non-human primate studies.

The high protective activity of the vaccine is achieved by co-expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) in the DNA vaccine used to prime the vaccine response. GM-CSF is a normal human protein that promotes the initiation of immune responses. By co-expressing GM-CSF and HIV proteins in the DNA vaccine, GM-CSF is present at the site of vaccination where it enhances the ability of the vaccine to elicit blocking antibodies for the virus. Blocking antibodies can stop a virus before it infects cells.

The vaccination regimen consisted of two DNA inoculations at months 0 and 2 to prime the vaccine response and then two booster inoculations at months 4 and 6. The booster vaccine was MVA, a recombinant poxvirus expressing HIV proteins. Six months after the last vaccination, both vaccinated and unvaccinated animals wer
'/>"/>

SOURCE GeoVax Labs, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. GeoVax Labs, Inc. Announces Six Month Financial Results and Provides Operational Update
2. GeoVax Labs, Inc. Information To Be Available Through Standard & Poors Market Access Program
3. GeoVax Presents Data at AIDS Vaccine 2008 Conference
4. GeoVaxs DNA and MVA Vaccines Shipped to HIV Vaccine Trials Network for Use in the Upcoming Phase 2a Trial
5. GeoVax Labs, Inc. Announces Third Quarter 2008 Financial Results and Provides Operational Update
6. GeoVax to Present at the BIO CEO & Investor Conference 2009
7. GeoVax to Webcast Its Presentation at the BIO CEO & Investor 2009 Conference
8. GeoVax Update Provided at the BIO CEO & Investor Conference 2009
9. GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2008 Financial Results
10. GeoVax Labs, Inc. Announces First Quarter Financial Results
11. GeoVax to Exhibit at the 2009 BIO International Convention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... July 31, 2014 Boston’s Adult Stem ... flush with innovative adult stem cell biotechnologies. Currently ... and has three additional patent applications currently under examination ... patented inventions address two of the most vexing problems ... Adult stem cells are difficult to identify; and ...
(Date:7/30/2014)... July 30, 2014 Regulus Therapeutics Inc ... leading the discovery and development of innovative medicines targeting ... and highlights for the quarter ended June 30, 2014 ... markets close. Regulus will host a ... at 5:00 pm Eastern Daylight Time to discuss its ...
(Date:7/30/2014)... 30, 2014 W. R. Grace ... of the REVELERIS® Prep purification system , ... chromatographers, and other researchers to perform both flash ... unit. , With the REVELERIS® Prep purification system, ... chromatography modes with a simple touch of the ...
(Date:7/30/2014)... A study presented at the 2014 ... of CSL Behring,s C1 Inhibitor (C1-INH) concentrate in ... sensitized patients. C1-INH is a human protein and ... The study shows that post-transplant treatment with ... of complement components 3 and 4, suggesting that ...
Breaking Biology Technology:The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 3Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 2Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 3Grace Launches New REVELERIS® Prep Purification System 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 3
... long-term promise, non-invasive techniques can also provide effective ... in the brain for paralyzed patients with significantly ... applications for healthy users. However, two issues hamper ... on non-invasive recording techniques, such as electroencephalography (EEG). ...
... IRVINE, Calif., Aug. 12 ChromaDex,Corporation, (OTC Bulletin ... contract research, today announced financial results for the,second ... in accordance with,U.S. Generally Accepted Accounting Principles (GAAP), ... of $0.03 per share for the,three months ended ...
... ST. LOUIS, Aug. 12 At the Board ... quarterly cash dividend of,$.13 per share. The dividend ... record on September 2, 2008., About Sigma-Aldrich: ... company. Our biochemical and organic chemical products and ...
Cached Biology Technology:ChromaDex Announces Second Quarter 2008 Financial Results 2ChromaDex Announces Second Quarter 2008 Financial Results 3
(Date:7/30/2014)... black truffle uses reversible epigenetic processes to regulate its ... ,methylome, - a picture of the genome regulation taking ... access journal Genome Biology and illustrates how ... and ,jumping genes,. The authors say this may shed ... controlled. , Black truffles (Tuber melanosporum), also known as ...
(Date:7/30/2014)... protected and tended her eggs until they hatched 4.5 ... 2014 in the open-access journal PLOS ONE ... and colleagues. , Octopuses typically have a single reproductive ... take care of their fertilized eggs until they hatch. ... to 3 months, but little is known about the ...
(Date:7/30/2014)... effects of climate change on the world,s animal ... factors, according to a new paper by a ... of Queensland, and other organizations. The authors claim ... the point when it comes to climate change. ... scientists focus on the "direct" threats of changing ...
Breaking Biology News(10 mins):How black truffles deal with the jumpers in their genome 2Deep-sea octopus has longest-known egg-brooding period 2Conservation scientists asking wrong questions on climate change impacts on wildlife 2
... and spend enormous resources on the conservation of endangered ... One big problem is international legislation and the need ... networks. Zoo resources can be spent much more effectively, ... animal collections across the world,s zoos. Many zoos ...
... and, in most cases, they have evolved a "circadian clock". ... has been shown to have important metabolic consequences for the ... on health; for example lack of sleep is linked with ... the ability to control body weight. Scientists from the ...
... Cell Research (ISSCR) has announced the following 2014 award ... Annual Meeting in Vancouver, taking place June 18-21, 2014: ... Research UK Gurdon Institute, for the McEwen Award for ... Yale Stem Cell Center, for the ISSCR-BD Biosciences Outstanding ...
Cached Biology News:Scientists warn: Conservation work in zoos is too random 2Scientists warn: Conservation work in zoos is too random 3The internal clock and feeding rhythm set the pace of the liver 2The International Society for Stem Cell Research announces its 2014 award recipients 2The International Society for Stem Cell Research announces its 2014 award recipients 3