Navigation Links
GeoVax Labs, Inc. Reports Data on Prototype Adjuvant - Supplemented HIV Vaccine Tested in Preclinical Animal Studies
Date:2/18/2010

th GM-CSF could actually prevent, not just control, HIV infections in humans."

The GM-CSF results were produced in a study using repeated rectal challenges with a dose of SIV that is 40 to 400 times the estimated typical dose of HIV associated with infections in humans.  Following 12 weekly infection attempts, all nine of the unvaccinated animals became infected, whereas only two of the seven animals vaccinated with the adjuvant-supplemented vaccine became infected.

"An ideal vaccine does not need an adjuvant and our vaccine currently in Phase 2a testing for prevention of HIV/AIDS does not contain one. However, with this recent success, we believe we have the data needed to support the design of an alternative HIV vaccine for GeoVax's product pipeline if our current vaccine does not provide good success," added Dr. Robinson.

GeoVax's mission is to develop both a preventative and therapeutic vaccine to combat HIV/AIDS.  Robert McNally, Ph.D., President and Chief Executive Officer, explained, "We are currently in a Phase 2a clinical trial with a vaccine that proved safe and immunogenic in Phase 1 testing. We are and continue to be optimistic about this product. The results from the adjuvant-supplemented product test suggest that we may have an effective alternative product should our non-adjuvanted vaccine prove suboptimal in expanded human clinical trials. This vaccine is being added to the patent portfolio of the company."

The work identifying the adjuvant activity of GM-CSF is supported by an NIH funded Integrated Preclinical/Clinical AIDS Vaccine Development program. Animal studies were completed at the Yerkes Primate Research Center in close collaboration with Drs. Lilin Lai and Rama Rao Amara. Investigators at Louisiana State University and Duke University also participated in the project.

About CR
'/>"/>

SOURCE GeoVax Labs, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. GeoVax Labs, Inc. Second Quarter Financial Results and Operational Update
2. U.S. Government Awards $15 Million Grant to GeoVax Labs HIV/AIDS Vaccine Program
3. GeoVax Further Strengthens Management Team
4. GeoVax Labs, Inc. Announces Six Month Financial Results and Provides Operational Update
5. GeoVax Labs, Inc. Information To Be Available Through Standard & Poors Market Access Program
6. GeoVax Presents Data at AIDS Vaccine 2008 Conference
7. GeoVaxs DNA and MVA Vaccines Shipped to HIV Vaccine Trials Network for Use in the Upcoming Phase 2a Trial
8. GeoVax Labs, Inc. Announces Third Quarter 2008 Financial Results and Provides Operational Update
9. GeoVax to Present at the BIO CEO & Investor Conference 2009
10. GeoVax to Webcast Its Presentation at the BIO CEO & Investor 2009 Conference
11. GeoVax Update Provided at the BIO CEO & Investor Conference 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Using a bio-mimicking analog of one of nature,s ... international research team led by Alejandro Briseno of ... major step in developing long-sought polymer architecture to ... use in electronic devices. , Briseno, with ... others at Stanford University and Dresden University of ...
(Date:9/30/2014)... 30, 2014 Shimadzu Scientific Instruments ... easy-to-use and highly precise tool for measuring displacement ... elongation. With 1000-mm maximum movement distance, the DSES-1000 ... a gauge length of 10 mm. In addition, ... above 50-mm stroke and within +/- 100 µm ...
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader in ... test built upon research from their published P.A.I.N. Study. ... physicians with an objective way to understand theirs patient’s ... individuals. With this new test, physicians will be able ... that will affect their pain tolerance. , The P.A.I.N. ...
(Date:9/30/2014)... -- CORD:USE Cord Blood Bank – www.corduse.com ... into an Equity and Exclusive Services Agreement with Tianhe Stem ... patented technologies for the isolation of human cord blood-derived ... performing Phase I/II clinical trials in China ... Tianhe,s Stem Cell Educator Therapy showing that the therapy ...
Breaking Biology Technology:Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 2CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 4
... BioSpace launched the ... showcasing biotechnological, pharmaceutical and medical device companies ... (Logo: http://photos.prnewswire.com/prnh/20040907/CLTU006LOGO) (Logo: http://www.newscom.com/cgi-bin/prnh/20040907/CLTU006LOGO) ... organizations within Oregon, Washington, Idaho and Montana ...
... Ridge Diagnostics, Inc., a neurodiagnostic company, announced that ... proprietary blood test for Major Depressive Disorder (MDD)  will ... Acceptance and Utility of a Multianalyte Biomarker Panel for ... The blood test, for the first time,  provides clinicians ...
... the second year in a row, a pair of ... Manufacturing Design Competition held by the American Society of ... Casey Hoffman and Jaron Kuppers won top honors in ... Elastomeric Tooling (SET) process. The SET process offers a ...
Cached Biology Technology:BioSpace Highlights the Northwest's Growing Life Science Region 2Ridge Diagnostics, Inc. Presents Clinical Data on Blood Test for Depression at U.S. Psychiatric and Mental Health Congress 2Rensselaer mechanical engineers win first place at ASME student manufacturing design competition 2Rensselaer mechanical engineers win first place at ASME student manufacturing design competition 3Rensselaer mechanical engineers win first place at ASME student manufacturing design competition 4
(Date:10/1/2014)... take a healthy salad up a level by growing ... in leafy greens. , "In the long run, one ... the salad or making a pill from the plant ... at Case Western Reserve School of Medicine and leader ... cancer organization is funding the research with a three-year, ...
(Date:9/30/2014)... of moorland burning is published today in the first ... of relieving tensions on both sides of the grouse ... Moorland Burning on the Ecohydrology of River basins) project ... practised predominantly to support red grouse populations for gun ... chemistry and physical properties, river water chemistry and river ...
(Date:9/30/2014)... WASHINGTON, D.C., September 30, 2014--Sea monkeys have captured the ... of their easily observable life cycle -- sold as ... and mate given little more than a tank of ... a shorter-term pattern: Like other zooplankton, brine shrimp vertically ... conditions, coming closer to the surface at night and ...
Breaking Biology News(10 mins):Scientists wield plant viruses against deadly human disease 2Scientists wield plant viruses against deadly human disease 3Grouse moor burning causes widespread environmental changes 2Laser-guided sea monkeys show how zooplankton migrations may affect global ocean currents 2
... responses, including insect outbreaks, wildfire, and forest dieback, may ... plants and animals. The U.S. Geological Survey ... warming world on "ecological thresholds" in North America. The ... Science Program and authored by a team of federal ...
... happening at a greater rate than other places in ... in the future. As a result, glacier and ... rise can be expected to continue. A new ... the first time the pervasive nature of Arctic climate ...
... epidemica (NE) has been linked to increases in the ... increased seedcrop production by broadleaf trees. Research published in ... Geographics links outbreaks of this rodent-borne disease to ... from the Department of Microbiology & Immunology at Belgium,s ...
Cached Biology News:Arctic heats up more than other places 2Global warming linked to European viral epidemic 2