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GeoVax Labs, Inc. Reports Data on Prototype Adjuvant - Supplemented HIV Vaccine Tested in Preclinical Animal Studies
Date:2/18/2010

ATLANTA, Feb. 18 /PRNewswire-FirstCall/ -- GeoVax Labs, Inc. (OTC Bulletin Board: GOVX) (the "Company"), an Atlanta-based, biopharmaceutical company developing vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus), today announced that it presented the results of a preclinical study on a prototype HIV/AIDS vaccine at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

The oral presentation, "Preclinical Studies on DNA/MVA Vaccines: Co-expressed GM-CSF, a Strong Adjuvant for Prevention of Infection," was presented by Dr. Harriet Robinson, Chief Scientific Officer for GeoVax and developer of the Company's vaccines. The study investigated the use of GM-CSF (granulocyte/macrophage colony-stimulating factor) as an adjuvant with the DNA prime for the GeoVax DNA/MVA vaccine for prevention of HIV/AIDS.

Adjuvants are agents that can increase the potency and effectiveness of a vaccine. GeoVax's work on adjuvants started in 2007. At that time, the National Institutes of Health (NIH) granted the company $15 million over five years to fund the search for any benefit derived from the use of adjuvants.  Results using GM-CSF showed protection from infection from simian immunodeficiency virus (SIV-monkey version of the HIV virus) in 70% of the seven exposed animals after 12 weekly exposures to the SIV virus.

"This is the highest level for prevention of an immunodeficiency virus infection ever reported in a non-human primate model," said Dr. Robinson. "We and other scientists originally thought it very difficult, even impossible, to completely prevent SIV infections. But based on the results from this study, we are now hopeful that our DNA/MVA vaccine supplemented wi
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SOURCE GeoVax Labs, Inc.
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