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HIV-1 vaccine. The breakthrough manufacturing technology developed
by Vivalis, through further development collaboration with GeoVax,
will create a new standard for manufacture of the MVA component of
GeoVax's HIV/AIDS vaccine. Vivalis' EBx(R) manufacturing platform,
with its increased effectiveness, superior quality and reliability,
is expected to better provide for MVA vaccine product availability
in ample quantities to meet sizeable demand and at a lesser cost.
Vivalis' vaccine manufacturing technology is based on a duck
embryonic stem cell substrate platform. Specifically, the EB66(R)
cell line provides continuous growth from a fully characterized
frozen cell bank, without necessitating fertilized embryo extraction
and processing, as with present chicken cell based technologies.
Furthermore, the EB66(R) cell line can be grown in suspension
(without the cells attached to the surface of the growth vessel) and
can be scaled up for growth in large bioreactors for commercial-
scale production of the MVA viral vaccine. The details of the final
license agreement between the parties are being negotiated and
GeoVax expects the final agreement to be executed before the end of
the year.
"On the financing front," Dr. McNally noted, "we are pleased with the
financing strategy provided by the $10 million common stock purchase
agreement with Fusion Capital Fund II, LLC, from which we are drawing in a
judicious manner, and we are also benefiting greatly from government
support in two ways -- from both the 5 year $15 million grant
(approximately $3 million awarded annually) initially awarded in October
2007 by the National Institutes of Health, and also from ongoing clinical
trial
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| SOURCE GeoVax Labs, Inc. Copyright©2008 PR Newswire. All rights reserved |