Navigation Links
Genzyme Files Applications for Approval of Mozobil in the United States and Europe
Date:6/17/2008

CAMBRIDGE, Mass., June 17 /PRNewswire-FirstCall/ -- Genzyme Corporation (Nasdaq: GENZ) announced today that it has submitted marketing applications in both the United States and the European Union for Mozobil(TM) (plerixafor), a product candidate intended to enhance mobilization of hematopoietic stem cells for collection and subsequent autologous transplantation in patients with lymphoma and multiple myeloma. The company has requested priority review of its U.S. application and, if granted, Mozobil could be approved by the end of this year. European approval is expected in 2009. Additional global applications in up to 60 countries are expected to follow.

Important Clinical Role

Mozobil is designed to mobilize stem cells from the bone marrow into the bloodstream where they can be collected, making it more likely for a patient with certain types of cancers to receive a successful transplant. Specifically, patients with non-Hodgkin's and Hodgkin's lymphomas and multiple myeloma often receive high-dose chemotherapy, a process that destroys bone marrow. A stem cell transplant is required to replenish blood-forming bone marrow cells destroyed by high-dose chemotherapy. Stem cells differentiate into the mature red blood cells, white blood cells, and platelets that a healthy person needs.

Currently, before a transplant can take place, patients may receive a prescribed dose of chemotherapy and/or other drugs, called growth factors, to help mobilize their hematopoietic stem cells into the bloodstream. Once the cells are released into the bloodstream, they are easier to collect in preparation for a transplant.

In order for the transplant to take place, a minimum number of approximately 2 million cells per kilogram of body
'/>"/>

SOURCE Genzyme Corporation
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Genzyme Boosts Quality Using Dyadem Quality Lifecycle Management
2. Awareness of Genzymes Renvela(R) (Sevelamer Carbonate) is High, Although Uptake of this New Phosphate Binding Agent has Been Slower than Nephrologists and Renal Dietitians Initially Expected
3. Genzyme Reports Strong First-Quarter Growth
4. Genzyme to Build New R&D Center in Beijing
5. Genzyme Provides Update on Myozyme(R) Manufacturing
6. Genzyme Withdraws Bioenvisions European Filing of Evoltra(R) in Elderly AML Patients
7. Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients
8. Genzyme and Isis Announce Hart-Scott-Rodino Approval of Collaboration
9. Genzyme and Isis Announce Strategic Alliance Including Exclusive Worldwide License of Mipomersen
10. BioMarin and Genzyme Restructure Aldurazyme 50/50 Joint Venture
11. Genzyme Receives European CE Mark for Single-Treatment Synvisc-One(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... May 23, 2013 PuraMed BioScience ® ... marketer of over-the-counter (OTC) medicinal and healthcare products, ... on the company based on low market capitalization ... Non-Prescription, All Natural Product to Treat Migraine Headaches ... #1 Prescription Competitor , Currently Available Nationwide ...
(Date:5/23/2013)... SAN MARINO, Calif. , May 23, 2013 ... announces today a strategic alliance with DAK Renewable ... increase the corn oil yield. VG Energy is ... Inc. (OTC Pink: VGLS). VG Energy,s ... pathways to increase the oil yield in plants, ...
(Date:5/23/2013)... On April 19th the Center for ... for the growing antibiotic resistant bacteria that may be ... long study were released late last month showing higher ... previous years. For those suffering from bacteria driven acne, ... bacteria in food, may eventually help breed acne causing ...
(Date:5/23/2013)... Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" and ... a teleconference to discuss its First Quarter 2013 financial ... information is provided below: Date: Thursday, May ... Dial-in: (800) 875-3456 (U.S.); (800) 648-0973 ( ... For those unable to participate in the ...
Breaking Biology Technology:PuraMed BioScience (PMBS) Issued Alert Based on Market Cap of $721,756 2PuraMed BioScience (PMBS) Issued Alert Based on Market Cap of $721,756 3VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 2VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 3Acne Cream, Probiotic Action Shares News on How Some Food may Breed Acne Causing Bacteria 2Pressure BioSciences, Inc. to Discuss First Quarter 2013 Financial Results and Provide Business Update 2
... to convert metallic wastes into high-value catalysts for generating ... of Microbiology . Researchers from the School ... the mechanisms that allow the common soil bacterium ... from industrial waste sources. Palladium is one of ...
... the National Institute of Standards and Technology (NIST) have ... measurementscritical data for a wide variety of fields dealing ... small as a few nanoliters. Currently a table-top prototype, ... for biotechnologists studying minute quantities of complex materials that ...
... Ont. (Wednesday, Sept. 1, 2010) - A new ... - developed by University of Waterloo engineering researchers ... such as medical devices, microelectromechanical systems (MEMS), printers, ... The breakthrough technology will provide engineers with ...
Cached Biology Technology:Metal-mining bacteria are green chemists 2Micro rheometer is latest Lab On a Chip device 2New process promises to revolutionize manufacturing of products 2
(Date:5/24/2013)... by avoiding detection and destruction by the immune system. ... cancer cells; however, there are many factors that cause ... cells are immune cells that function to suppress the ... Journal of Clinical Investigation , researchers led by Ronald ... that infiltrate tumors express proteins that can be targeted ...
(Date:5/23/2013)... , Automated conserved noncoding sequence (CNS) discovery reveals ... , Within the genome of each species, there ... change in position and sequence over millions of years, ... these evolutionarily stable sequences, so-called conserved noncoding sequences (CNSs), ... or the condensation of chromosomes, but the function of ...
(Date:5/23/2013)... mechanism by which estrogen suppresses lipid synthesis in the ... approach toward treating certain liver diseases. , With ... are changing long-held views in the field. Study results ... Science Signaling . , "The dogma in the ... only receptors located in the nucleus respond to steroid ...
Breaking Biology News(10 mins):Frontiers news briefs: May 23 2Frontiers news briefs: May 23 3UCI study reveals new mechanism for estrogen suppression of liver lipid synthesis 2
... 2008) -- Scientists and researchers have taken a big ... strain of avian influenza, or "bird flu," the potential ... infected nearly 400 people in 14 countries since it ... Department of Energy,s (DOE) Argonne National Laboratory, in conjunction ...
... last 10 years has seen a huge increase in the ... being kept in our homes are monkeys, tarantulas, iguanas, salamanders, ... reserves around the world develop their conservation and captive breeding ... husbandry of exotic animals. To help develop ...
... 2008 A systematic literature review conducted by a ... Hispanic Health Council (Hartford), and the Connecticut Center for ... peer education/counseling on nutrition and health outcomes among Latinos ... the July/August issue of the Journal of Nutrition ...
Cached Biology News:Newly described 'dragon' protein could be key to bird flu cure 2The exotic side of veterinary science 2The exotic side of veterinary science 3Peers important for nutrition education among Latinos 2
... Protein determined by Biuret. Physical ... (NH 4 ) 2 SO ... Note: Affinity purified • Physical ... Additives: MgCl 2 1 ...
... MW: 60kDa (A) and 36kDa (C) ... pH 7.5, 500mM NaCl, 60mM 2-mercaptoethanol, ... 1mM DTT, and 0.1mg/ml serum albumin ... of proteins. Purification: DEAE chromatography, aminohexyl-agarose ...
... IT siRNA Tracker Intracellular Localization Kit provides ... and deliver siRNA, of your design, in ... vitro tracking experiments. Subcellular localization and functional ... monitored following introduction of the labeled siRNA ...
Selective media for Salmonella...
Biology Products: