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Genzyme Begins Major Expansion of Boston Manufacturing Facility
Date:9/18/2007

S. Securities and Exchange Commission, including without limitation the factors discussed under the caption "Risk Factors" in Genzyme's Quarterly Report on Form 10-Q for the fiscal quarter ended June 30, 2007. We caution investors not to place undue reliance on the forward-looking statements contained in this press release. These statements speak only as of the date of this press release, and we undertake no obligation to update or revise the statements.

Genzyme's press releases and other company information are available at http://www.genzyme.com and by calling Genzyme's investor information line at 1-800-905-4369 within the United States or 1-678-999-4572 outside the United States.

Genzyme(R), Renagel(R), Myozyme(R), Cerezyme(R), Fabrazyme(R), Thyrogen(R) and Aldurazyme(R) are registered trademarks of Genzyme Corporation or its subsidiaries. All rights reserved.

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