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Genstruct Added to The Biomarker Consortium's Rapidly Growing Roster of Industry Experts
Date:11/4/2008

of compound mechanisms of action (MOA) and biomarkers of safety and efficacy. Its scientists leverage the system and methodologies for internal research programs as well as research partnerships with pharmaceutical companies in order to streamline drug discovery and development and improve clinical trial design and implementation.

Dr. Elliston added, "We have initially focused on three core disease areas at Genstruct: oncology, metabolic disorders and inflammation. These are all key areas of research for The Biomarker Consortium as well. We believe that the identification of molecular mechanisms and mechanistic biomarkers in these disease areas through systems biology approaches will ultimately lead to better decisions, lower product failure rates, optimal clinical trial design and execution and faster FDA product approval."

About Genstruct

Founded in 2002, Genstruct is a systems biology company focused on elucidating the complexity of biology for the development of safe and effective therapeutics and molecular diagnostics. By developing Causal Network(TM) models for complex biological systems, Genstruct develops a deep molecular understanding of diseases and drug action, and designs mechanistic biomarkers and molecular diagnostics to facilitate drug development and personalized medicine. Genstruct's Consulting Services division engages in short-, mid- and long-term partnerships with top tier pharmaceutical and life sciences companies, to develop new therapeutics and mechanistic biomarkers in the areas of oncology, metabolic disorders, cardiovascular diseases and inflammation. Genstruct was awarded the Bio-IT World 2008 Best Practices Award in the Drug Discovery & Development category for its joint collaboration with Sirtris Pharmaceuticals (a GSK company). Genstruct is a privately held company based in Cambridge, Mass. For more information, please visit http://www.genstruct.com.

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