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Genomic Health and OncoMed Announce Strategic Alliance for Biomarker Research and Discovery Using Next Generation Sequencing
Date:5/2/2012

REDWOOD CITY, Calif., May 2, 2012 /PRNewswire/ -- Genomic Health, Inc. (Nasdaq: GHDX) and OncoMed Pharmaceuticals, Inc. (OncoMed) today announced a strategic alliance to use Next Generation Sequencing (NGS) to identify biomarkers that can be applied to the clinical development of OncoMed's  novel antibody cancer therapeutics.

Under the terms of the agreement, OncoMed will provide Genomic Health with breast, prostate, colon and lung tumor samples.  A subset of these tumors will include OncoMed's extensive bank of proprietary xenograft models derived from freshly resected human cancers. Genomic Health will apply its industry-leading NGS capabilities; including proprietary sample preparation, high-throughput sequencing and bioinformatics, to discover biomarkers that can help identify subsets of patients that will more likely respond to cancer therapeutics targeting the Notch, Wnt and other pathways critical to cancer stem cells.

"Working with like-minded, innovative cancer companies, we can utilize our proven NGS-based diagnostic research and development infrastructure to help optimize patient selection to accelerate clinical development of targeted cancer treatments," said Steven Shak, M.D., chief medical officer, Genomic Health. "This collaboration supports our long-term vision and belief that, molecular diagnostics are inherent for bringing quality, personalized care to all cancer patients from diagnosis through survivorship."

"Our priority is not only to develop therapeutic antibodies but to target their clinical use in the subsets of patients most likely to benefit through focused clinical plans, which include patient selection strategies at early stages of testing," said Paul J. Hastings, president and chief executive officer of OncoMed. "We believe the collaboration with Genomic Health will accelerate our already existing efforts of developin
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SOURCE Genomic Health, Inc.
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