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Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test
Date:3/17/2011

REDWOOD CITY, Calif. and ST. GALLEN, Switzerland, March 17, 2011 /PRNewswire/ -- Genomic Health, Inc. (Nasdaq: GHDX) today announced results from nine studies utilizing the Oncotype DX® test in early-stage breast cancer patients at the 12th Annual St. Gallen International Breast Cancer Conference in St. Gallen, Switzerland.  The studies included region-specific decision impact data that demonstrated the knowledge of a patient's Recurrence Score® (RS) result changed physicians' treatment recommendations in approximately 33 percent of cases in the United Kingdom (UK), Germany and Spain, which is similar to what has been shown in United States. Health economic data that illustrated the cost effectiveness of utilizing the RS result in Greece, Hungary and Singapore were also presented.

"We have now presented or published results from 11 decision impact studies conducted in five countries that emphasize the independent value of the Recurrence Score to identify which early-stage breast cancer patients can use hormonal therapy alone and forego chemotherapy, as well as those who should also be treated with chemotherapy," said Steven Shak, chief medical officer at Genomic Health.  "The consistency of these results demonstrating that the Oncotype DX breast cancer test changes treatment decisions in approximately a third of cases, combined with positive cost-effectiveness analyses, supports our efforts to gain broad public reimbursement coverage for the test and expand this critical service to breast cancer patients worldwide."

The Oncotype DX breast cancer test measures the expression of 21 genes of an individual breast cancer tumor to generate a RS that quantifies the magnitude of chemotherapy benefit and the likelihood of recurrence for early-stage patients.  The test was launched in the United States in 2004 where it has been widel
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SOURCE Genomic Health, Inc.
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