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Genomic Health Announces Multiple Colon Cancer Studies at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium
Date:1/21/2011

REDWOOD CITY, Calif., Jan. 21, 2011 /PRNewswire/ -- Genomic Health, Inc. (Nasdaq: GHDX) today announced presentation of three studies at the American Society of Clinical Oncology® (ASCO®) (1) Gastrointestinal (GI) Cancer Symposium, including one finding that high tumor grade was not a marker of higher recurrence risk in stage II colon cancer, suggesting that other markers, such as the Oncotype DX® Recurrence Score® (RS) test as well as T-stage and mismatch repair (MMR) status, should be considered by physicians during the treatment decision-making process.

"These results presented at ASCO-GI reinforce the value that the Oncotype DX Colon Cancer test provides to physicians, patients and payors," said Steven Shak, M.D., chief medical officer of Genomic Health.  "The Oncotype DX Colon Cancer test, which has been commercially available for the past year, combines the practicality of paraffin-embedded tumor tissue with robust evidence from multiple large independent development and validation studies focused on the specific clinical questions relevant to physicians and patients.  Rigorous comparison of the colon cancer test with conventional markers of recurrence risk, including MMR and T-stage, has demonstrated its independent value.  These data allow physicians and patients to confidently and appropriately incorporate information about individual tumor biology provided by Oncotype DX into treatment decisions in stage II colon cancer.  As with our breast cancer program, we are committed to increasing the clinical utility of our colon cancer franchise through continued research and look forward to expanding the Oncotype DX service by offering MMR testing this year."

Comparative Study Supports Independent Determination of MMR Status by IHC

Previous research suggests that stage II colon cancer patients with deficient mismatch repair (MMR-D) have significantly fewer re
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SOURCE Genomic Health, Inc.
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