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Genomatica Delivers Pilot-Scale Validation in Sustainable Chemical Manufacturing
Date:6/29/2010

targets required to produce Genomatica's green BDO at lower cost than typical commercial production of petroleum-based BDO.

The scale-up to 3,000 liters, a 100-fold increase from lab scale, was completed in two months. Results matched metrics from smaller-scale tests, and from Genomatica's modeling software. The scale-up was performed at MBI, a not-for-profit technology company affiliated with Michigan State University's BioEconomy Network, which has worked with companies including DuPont Applied BioSciences. "MBI's deep experience with scale-up and de-risking made them a great partner," said Mark Burk, chief technology officer of Genomatica.

Unique Development Platform Slashes Time to Market

Genomatica created and used its unique integrated bio-process engineering platform to develop its BDO organisms and complete manufacturing process. This was achieved in a record 2 1/2 years – dramatically faster than previous industry accomplishments with bio-processes.

Genomatica's platform allows high-throughput 'in-silico' (computer-based) design and testing of highly-optimized organisms, manufacturing processes and economics. This results in more efficient, focused lab work, much faster product development and time to commercial-scale manufacturing, lower-cost production, and de-risking of the process. Genom
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