Navigation Links
Genmab and Pepscan to Identify Human Antibodies Against Intractable Targets
Date:3/3/2008

COPENHAGEN, Denmark and LELYSTAD, Netherlands, March 3 /PRNewswire-FirstCall/ -- Genmab A/S (OTC: GNMSF) and Pepscan today announced the start of a research collaboration aimed at identifying fully human monoclonal antibodies against intractable disease targets. Intractable targets include those that are difficult to address using commonly available technologies but are highly desirable for targeting with monoclonal antibodies. These difficulties can for example be due to the fact that target proteins are buried to a large extent very close to the cell surface or in the cell membrane or due to poor immunogenicity of the protein or desirable epitopes.

In the collaboration, Pepscan will use its proprietary CLIPS(TM) technology to identify functional mimics of the essential parts of such intractable targets. These mimics will be used by Genmab to create and select unique therapeutic antibodies using its fully human monoclonal antibody technology.

"As part of our efforts to expand Genmab's pipeline, we continually evaluate disease targets which may effectively be addressed with monoclonal antibodies," said Lisa N. Drakeman Ph.D., Chief Executive Officer of Genmab. "This research collaboration with Pepscan will allow us to include in our evaluations a wider variety of disease targets that may not be easily addressed using standard treatments."

Joost van Bree, CEO of Pepscan Therapeutics comments: "monoclonal antibodies against intractable targets are a significant unmet need. The combination of Pepscan CLIPS(TM) protein mimicry platform with Genmab's ability to generate fully human monoclonals will enable the partners to develop innovative products for poorly served indications."

About Genmab A/S

Genmab is a leading international biotechnology company focused on developing fully human antibody therapeutics for unmet medical needs. Using unique, cutting-edge antibody technology, Genmab's world class discovery and development teams
'/>"/>

SOURCE Genmab and Pepscan Therapeutics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Genmab and PDL BioPharma Sign Purchase Agreement for Antibody Manufacturing Facility
2. Medarex Announces Completion of Sale of Shares in Genmab A/S
3. Genmabs Financial Calendar for 2008
4. Genmab Reaches Milestones in Ofatumumab Collaboration
5. Genmab Announces HuMax-CD32b Pre-Clinical Program
6. Roche Files IND for Second Genmab Antibody
7. Genmab A/S - R1507 Antibody to Enter Phase II Study to Treat Sarcoma
8. Genmab Announces Details of Planned Ofatumumab Phase II Study in Multiple Sclerosis
9. Fourth Genmab Antibody Developed Under Roche Collaboration to Enter Clinic
10. Genmab Announces Update on Recruitment of Patients in ofatumumab CLL Pivotal Study
11. Genmab Announces Results for the First Nine Months of 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... -- This report analyzes the worldwide markets for Bioinformatics in ... Biocontent. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2013 ... these markets. Market data and analytics are derived from primary ...
(Date:9/16/2014)... September 16, 2014 --The emerging field of molecular ... the next level, enabling the construction of tiny ... devices, individual molecules would take on the roles ... , A team of researchers from five Japanese ... for use in small-scale electronics: a molecule called ...
(Date:9/16/2014)... BlueInGreen® , a water quality company ... dissolved gases into liquids, announced the addition of ... representative firm to its sales network. H2Flow will ... and wastewater applications in the Canadian provinces of ... 1992 and serves Quebec and Ontario markets for ...
(Date:9/16/2014)... 16, 2014 CIRTEC Medical Systems’ Board ... as CEO of CIRTEC. , “I am delighted ... the Company.” noted Brian Highley. “The company has made ... strong organic growth over the past two years. The ... to improve and expand the services Cirtec offers its ...
Breaking Biology Technology:Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23The future face of molecular electronics 2BlueInGreen® Expands into Canada – Signs Representative Agreement with H2Flow Equipment Inc. 2
... Sept. 26 MacroGenics, Inc. announced,today that Mr. ... of the,company,s Board of Directors. With more than ... in the pharmaceutical and,biotechnology industry, Mr. Buchalter is ... MacroGenics as the company matures toward,commercializing its pipeline. ...
... XTL,Biopharmaceuticals Ltd. (NASDAQ: XTLB ; LSE: ... 2007, the Company received a NASDAQ Staff,Determination indicating ... minimum,$10 million shareholders, equity requirement for continued listing ... Marketplace Rule 4450(a)(3), and that,its ADRs are, therefore, ...
... Empowers Life Sciences Community with accelerated BioInformatics, ... Corp., announced,the initiation of Progeniq Pte Ltd, ... Singapore, into the BioIT Alliance today. The,BioIT ... integrate science and,technology to accelerate the pace ...
Cached Biology Technology:Jeffrey H. Buchalter Joins MacroGenics Board of Directors as Chairman 2Jeffrey H. Buchalter Joins MacroGenics Board of Directors as Chairman 3XTL to Appeal NASDAQ Staff Determination; XTL May Transfer its ADR Listing to the NASDAQ Capital Market 2XTL to Appeal NASDAQ Staff Determination; XTL May Transfer its ADR Listing to the NASDAQ Capital Market 3Progeniq Joins Microsoft in Bio IT Alliance 2Progeniq Joins Microsoft in Bio IT Alliance 3
(Date:9/16/2014)... a 10-km diameter chunk of rock hit the Yukatan peninsula ... the force of 100 teratons of TNT. It left a ... wildfires, global earthquakes and volcanism are widely accepted to have ... of the mammals. But what happened to the plants on ... researchers from the University of Arizona reveals that the meteorite ...
(Date:9/16/2014)... (KXL) would likely increase oil sands extraction, according to ... non-profit organization Near Zero. The results are detailed in ... both supporters and opponents of the pipeline. ... to significantly higher greenhouse gas emissions, with the exact ... "This report examines three main scenarios discussed by participants ...
(Date:9/16/2014)... its extravagant, colorful tail feathers in courtship of a ... special camera developed by an engineer at Washington University ... fish choose their mates based on a similar display. ... Austin used a bioinspired polarization camera developed by Viktor ... at Washington University, to make the discovery. His camera ...
Breaking Biology News(10 mins):Meteorite that doomed the dinosaurs helped the forests bloom 2Meteorite that doomed the dinosaurs helped the forests bloom 3Keystone XL would likely raise oil sands production and greenhouse gas emissions 2Camera developed at WUSTL sheds light on mate choice of swordtail fish 2
... Research led by T. Cooper Woods, PhD, Assistant Professor ... Center New Orleans, and Director of the Molecular Cardiology ... mechanism of how a drug commonly used on stents ... movement which is critical to wound healing and the ...
... TORONTO (April 13, 2010) -- An investigational intervention using ... thinking abilities of a group of mild- to moderate-stage ... rate of atrophy (shrinkage) of their brains, according to ... Center. These and other findings from the Phase II ...
... the Department of Computer Science at Virginia Tech have used ... by scientists in their quest to define the microbial DNA ... computers from across the world, the mpiBLAST computational tool used ... 90 years it would have required if the work were ...
Cached Biology News:Research discovery may lead to advances in heart disease and cancer treatment 2Investigational immune intervention slows brain shrinkage in Alzheimer's patients 2Investigational immune intervention slows brain shrinkage in Alzheimer's patients 3Investigational immune intervention slows brain shrinkage in Alzheimer's patients 4High-performance computing reveals missing genes 2High-performance computing reveals missing genes 3
...
... The Bio-Plex maintenance, calibration, ... is a custom 96-well plate ... validation, and calibration procedures using ... This MCV plate is for ...
Mynox is intended for research use only. Mynox is used for the elimination of Mycoplasma and Acholeplasma in cell and virus cultures, and other biologicals....
... PCR detection system holds 48 x 0.2 ml ... 48 LEDs independently excites fluorescence (470-500 nm) for ... detects emitted light (523-543 nm and 540-700 nm). ... cycler, whose Peltier heat pumps provide superb thermal ...
Biology Products: