Navigation Links
Genetic Engineering & Biotechnology News Reports on Growing Use of Cell-Based Assays
Date:4/16/2008

NEW ROCHELLE, N.Y., April 16 /PRNewswire/ -- Biotech and pharma companies are increasingly relying on cell-based assays in early drug discovery work, reports Genetic Engineering & Biotechnology News (GEN). The technique can provide a quick and lower cost means of testing drug candidates for toxic effects, according to an article in the April 15 issue of GEN (http://www.genengnews.com/articles/chitem.aspx?aid=2437).

"Better screening technologies, noninvasive monitoring, and more automation are driving the trend toward adoption of this technology," notes John Sterling, Editor-in-Chief of GEN. "Some estimates project that the market for cell-based assays will more than double over the next six or seven years to over $230 million. This is definitely a methodology that should draw the interest of new drug developers."

More than 50% of currently marketed drugs target GPCRs, which impact a wide range of cellular processes. Multispan is looking to exploit this area and is collaborating with Promega and Molecular Devices to develop an array of applications for its GPCR cell-based assays.

Another field of much R&D interest involves protein-protein interactions. DiscoveRx created a new family of cell-based assays for the detection of protein-protein interactions using an enzyme fragment complementation assay. This system uses an enzyme acceptor, an inactive alpha-galactosidase enzyme that binds to its enzyme donor forming an active enzyme that will hydrolyze a substrate and provide a signal.

Other companies covered in the GEN article include Merck Research Laboratories, Sophion, Nanion, Novo Nordisk, ACEA Biosciences, and AstraZeneca.

For a copy of the April 15 issue of GEN, please call (914) 740-2122, or email: ebicovny@liebertpub.com

Genetic Engineering and Biotechnology News

SOURCE Genetic Engineering and Biotechnology News
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Digital Unions RT1(TM) Software Creates Telegenetics Network for Region 3 Genetics Collaborative
2. Response Genetics Reports Second Quarter 2007 Financial Results
3. ZymoGenetics Will Hold Conference Call Today at 5:00 p.m. Eastern Time to Provide Update on rThrombin
4. Clinical Data Acquires Epidauros Biotechnologie AG, Significantly Enhancing Proprietary Genetic Biomarker Portfolio
5. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
6. deCODE genetics to Webcast Presentation at Thomas Weisel Partners Annual Healthcare Conference
7. ZymoGenetics to Webcast Presentation at Two Upcoming Conferences
8. Interleukin Genetics Announces Management and Board Appointments
9. Response Genetics Announces Presentations/Webcasts at Upcoming Investor Conferences
10. Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference
11. CellCyte Genetics Corp. Forms Device Division to Develop and Manufacture Stem Cell Cultivation and Replication Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... the sound-processing part of the mouse brain in a ... trees in view. Their imaging technique allows zooming in ... and it enabled the team to watch brain cells ... results, which represent a step toward better understanding how ... the journal Neuron . , In the past, ...
(Date:7/31/2014)... 31, 2014 Rogne Bioscience, a privately-held biotechnology ... , has acquired a licence to anti-inflammatory peptides ... The potent anti-inflammatory activity of the peptides was discovered ... of Oxford,s Sir William Dunn School of ... over $1.5 million in seed financing, is developing a ...
(Date:7/31/2014)... , July 31, 2014 Research and ... "Global Genomics Market 2014-2018" report to their offering. ... Genomics is the study of the genetic material or ... a strong basis for the discovery and development of ... diseases or health conditions. Genomics is supported by three ...
(Date:7/31/2014)... SHENZHEN, China , July 31, 2014 ... an Irys™System by BGI , the ... enable comprehensive exploration of human structural variation (SV) and ... interest, including those where no reference exists. In addition, ... methods for multiplexing on the Irys System, enabling significantly ...
Breaking Biology Technology:New mapping approach lets scientists zoom in and out as the brain processes sound 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2BioNano Genomics Announces the Purchase of the Irys System by BGI 2BioNano Genomics Announces the Purchase of the Irys System by BGI 3BioNano Genomics Announces the Purchase of the Irys System by BGI 4
... May 2, 2012 Genomic Health, Inc. (Nasdaq: ... announced a strategic alliance to use Next Generation Sequencing ... the clinical development of OncoMed,s  novel antibody cancer therapeutics. ... will provide Genomic Health with breast, prostate, colon and ...
... Ga., May 2, 2012   MiMedx Group, Inc.   (OTCBB: ... regenerative biomaterials and bioimplants processed from human amniotic membrane, announced ... , Revenue Increases over 250% ... First Time in Company History , ...
... created artificial muscles that can be transformed at the ... abilities of organisms such as squid and zebrafish. ... could be used in ,smart clothing, to trigger camouflaging ... The study is published today, 2 May, in IOP ...
Cached Biology Technology:Genomic Health and OncoMed Announce Strategic Alliance for Biomarker Research and Discovery Using Next Generation Sequencing 2Genomic Health and OncoMed Announce Strategic Alliance for Biomarker Research and Discovery Using Next Generation Sequencing 3Genomic Health and OncoMed Announce Strategic Alliance for Biomarker Research and Discovery Using Next Generation Sequencing 4MiMedx Group Announces Record First Quarter Results 2MiMedx Group Announces Record First Quarter Results 3MiMedx Group Announces Record First Quarter Results 4MiMedx Group Announces Record First Quarter Results 5MiMedx Group Announces Record First Quarter Results 6MiMedx Group Announces Record First Quarter Results 7MiMedx Group Announces Record First Quarter Results 8MiMedx Group Announces Record First Quarter Results 9Squid and zebrafish cells inspire camouflaging smart materials 2
(Date:7/31/2014)... models against the highly infectious and virulent bacterium, ... kills approximately 30,000 Americans annually. The research is published ... , In the study, the vaccine protected the ... by C. difficile , as well as from ... the human disease, after only two immunizations. , ...
(Date:7/31/2014)... week that the U.S. surgeon general issued a 101-page ... Montana State University published a paper breaking new ground ... cell responds when exposed to ultraviolet (UV) light. ... by the UV rays found in sunlight. This damage ... eye diseases. , "Our paper advances foundational knowledge ...
(Date:7/31/2014)... and beige adipocytes, or fat cells, are inherently different. ... each plays its own role in metabolism. In the ... most prevalent. Its primary function is energy storage. On ... generate heat but are only found in a few ... represent a special type of brown adipocytes, appear mixed ...
Breaking Biology News(10 mins):C. difficile vaccine proves safe, 100 percent effective in animal models 2New paper describes how DNA avoids damage from UV light 2New paper describes how DNA avoids damage from UV light 3Hope for the overweight 2
... international study based at the University of Pittsburgh provides ... biodegrade carbon nanotubesthe superstrong materials found in products from ... damaging health effects of being exposed to the tiny ... Nanotechnology . The results could open the door ...
... interested in moray eels in 2005 when he was applying to ... him on a campus tour, his host, Brian Bowen, PhD, a ... southwest coast of Oahu, Reece looked under a rock ledge and ... back. When he later captured the eels, he found the same ...
... Sean E. McLean, MD, has been selected as a ... Harold Amos Medical Faculty Development Program is a national program ... professor of pediatric surgery in the University of North Carolina ... 11 nationwide selected this year to receive the award. Harold ...
Cached Biology News:Pitt-led study identifies human enzyme that breaks down potentially toxic nanomaterials 2Pitt-led study identifies human enzyme that breaks down potentially toxic nanomaterials 3Cosmopolitan eels 2Cosmopolitan eels 3Cosmopolitan eels 4Cosmopolitan eels 5
... Rapid-Screen cDNA Library Panels were designed for ... sets of PCRs to identify the desired ... performed in a 96-well "Master Plate," where ... clones. Having identified the positive well(s) by ...
... Unique, compact measuring instrument for calibrating ... compact design and the robust carrying case, ... both in the laboratory and on-site at ... easy to use because the individual channels ...
... HVJ (hemagglutinating virus of Japan, also ... a tool for transfection of molecules by ... are for siRNA (RNAi), Protein, Oligo, cDNA, ... and in vivo. GenomONE-Neo EX has a ...
... S. pombe Whole Genome ChIP-on-chip Microarray ... of yeast (S. pombe) DNA binding ... with Agilent DNA microarrays. This set ... data with greater true binding events ...
Biology Products: