Navigation Links
Genethon and Children's Hospital Boston Get FDA approval for a Wiskott Aldrich Gene Therapy Trial
Date:7/21/2011

f Translational Research for Children's Hospital Boston, will serve as sponsor-investigator. The gene insertion of patient cells will be accomplished in the Connell O'Reilly Family Good Manufacturing facility at the Dana-Farber Cancer Institute in collaboration with the Center for Human Cell Therapy at Harvard Medical School.

Wiskott Aldrich Syndrome (WAS) is a rare primary immune deficiency disease causing significant bleeding due to low platelet count and increased incidence of serious infections.  Most patients have mild to severe eczema and are also at a higher risk of developing autoimmune disorders and malignancies such as lymphoma.  The forthcoming clinical trial results from a research program initiated in 2002 by the group of Anne Galy at Genethon (Inserm UMR951/Genethon, Universite d'Evry Val d'Essonne, EPHE), which has developed an ex vivo approach that uses an HIV-derived lentiviral vector to transfer genes into autologous CD34+ hematopoietic stem cells from WAS patients.

"This authorization constitutes a new key stage for the project WAS initiated in 2002 by Anne Galy and her team at the Genethon. It is also an international recognition of the quality of the work of Genethon. Without the donations collected during the French Telethon, this international gene therapy trial could not exist," states Laurence Tiennot-Herment, Chairperson, AFM and Genethon. 

"We are very happy with the approval given by the FDA for the extension of the WAS clinical trial by the group headed by Prof. Williams. It demonstrates again the ability of Genethon to bring its research projects to the clinic in collaboration with the best clinical teams worldwide, for the benefit of patients. It reflects our cutting edge expertise in the field of translational research, bioproduction and preparation and implementation of clinical trials," emphasizes Frederic Revah, CEO Genethon.

"At Children's Hospital Boston,
'/>"/>

SOURCE Children's Hospital Boston
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Pradaxa® (dabigatran etexilate mesylate) Capsules Now on Formulary at Nations Top Heart Hospitals
2. Axial Biotech Signs Agreement With Shriners Hospital for Children
3. Texas Childrens Hospital is First Pediatric Hospital in the Nation to Implant Artificial Heart
4. Paoli Hospital Pioneers New Treatment for Uterine Fibroids and Malformations
5. Baylor College of Medicine and Texas Childrens Hospital Neuroscientist Dr. Huda Zoghbi Awarded Gruber Neuroscience Prize
6. Hospital for Special Surgery to Host International Arthritis Summit: Frontiers in Osteoarthritis Research, Prevention and Care
7. St. Lukes Hospital & Health Network Selects CareTech Solutions to Provide Proactive Monitoring of Hospital IT Infrastructure
8. BioNeutral to Premier its EPA-Approved Ygiene® 206 Hospital-Grade Disinfectant at the Annual 2011 APIC Conference, While Community Health of South Florida Begins Product Review
9. SynapDx Corporation Licenses Autism Diagnostic Discoveries From Childrens Hospital Boston
10. Newly Published Study Shows Dramatic Reduction in Hospital Acquired Infections
11. WARFARIN Study Launched at WellStar Health System to Assess Impact of Genetic Testing in Reducing Hospitalizations and Deaths Caused by Warfarin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/25/2015)... MN (PRWEB) March 26, 2015 Agnition ... upcoming episode of American Farmer, airing for the first ... The segment of American Farmer will explore the extremely ... provides crop producers with a patented Microbial Catalyst™ technology ... and greater yields. The segment will air again on ...
(Date:3/25/2015)... The surging prevalence of internet ... social media growth, with over 50% of the ... networking. Insurance companies are making use of social ... promote a diversity of their services and products. ... social networking services as part of sales and ...
(Date:3/25/2015)... , March 25, 2015 Accelovance, a therapeutically ... finalist for "Best Contract Research Organization" at the upcoming ... Vaccine Congress. This is the eighth ... for the award, winning for "Best Contract Research Organization" ... Recommended" distinction in 2013. "We,re excited to ...
(Date:3/25/2015)... Fla. , March 25, 2015  Point-of-Care ... and management consulting firm, has launched the ePrescribing ... to simplify tracking of ePrescribing regulatory requirements in ... "The ePrescribing regulatory landscape continues to change rapidly, ... deliver what the industry, and ultimately patients, need," ...
Breaking Biology Technology:Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2Point-of-Care Partners Launches the ePrescribing State Law Capsule 2
... March 23 Nereus Pharmaceuticals, Inc., a pioneer ... announced that it is conducting a randomized Phase ... (VDA) NPI-2358 in combination with standard chemotherapy (docetaxel) ... This study follows on positive outcomes in ...
... Corporation (Nasdaq: PRXL ), a leading ... Company has received the Best Performing Clinical Research ... for life sciences businesses encouraged by the Economic ... to PAREXEL at the BioSingapore Asia/Pacific Biotechnology Awards ...
... York, December 1, 2008 Although naturally occurring smallpox ... might obtain smallpox from a laboratory and release it ... smallpox vaccine may be insufficient for universal administration. In ... The American Journal of Medicine , researchers found ...
Cached Biology Technology:Nereus Pharmaceuticals Initiates ADVANCE, a Randomized Phase 2 Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer 2Nereus Pharmaceuticals Initiates ADVANCE, a Randomized Phase 2 Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer 3PAREXEL Receives BioSingapore Award for Best Performing CRO 2PAREXEL Receives BioSingapore Award for Best Performing CRO 3PAREXEL Receives BioSingapore Award for Best Performing CRO 4New study indicates smallpox vaccination effective for decades 2
(Date:3/23/2015)... 23, 2015 SoundView Technology Group issues a new ... NXTD ) Wocket smart wallet. SoundView was one of the selected ... experience with the Wocket in multiple scenarios and outlets. ... and other retailers, making both debit and credit card payments.  ... says, "If the company meets their plans in 2015, it ...
(Date:3/20/2015)... 20, 2015 Research and Markets ... the "India Sensors Market Forecast and Opportunities ... The sensor market is projected to grow at ... Consumer electronics, automotive, industrial and healthcare sectors are ... country. In addition, adoption of MEMS technology in ...
(Date:3/19/2015)... , March 19, 2015  NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market, announces its biometric ... news clip that aired this week on Washington ... In a segment "The Next Great Thing", host ... new way to pay, and ,a really big breakthrough in ...
Breaking Biology News(10 mins):Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... and partnering organizations have discovered a remarkably primitive eel in ... Palau. This fish exhibits many primitive anatomical features unknown in ... living eels, resulting in its classification as a new species ... is published online in the Proceedings of the Royal ...
... mice exposed to prenatal stress are more sensitive to stress ... issue of The Journal of Neuroscience . These findings ... in stress response that may be passed across generations. ... previously found that male mice were sensitive to stress their ...
... Switzerland have investigated the remarkable distance that microorganisms may ... their potential to colonise new lands and also potentially ... Moores University (LJMU), Swiss Federal Institute for Forest, Snow ... de Lausanne (EPFL) the University of Neuchtel published their ...
Cached Biology News:Scientists discover the most primitive living eel 2Effects of prenatal stress passed across generations in mice 2Life on the wind: Study reveals how microbes travel the Earth 2
... Disposable, clear, APET plastic tray. Ideal for ... those trays used for multipurposes. Pour spouts ... A marker or label may be used ... trays on rockers or shakers for staining ...
... The Staccato Series of systems provide ... today's drug discovery, genomics, proteomics and ... available in three base configurations; Mini ... Systems Series. All Staccato Application ...
... microfiltration devices for the fast and reliable clarification/filtration ... to 500 l. They can be used in ... Product Features: High-flux Polyethersulphonemembrane ... up volume ( Fast and reproducible performance ...
... Staccato Series of systems provide fast and reliable scalable ... drug development laboratories. Staccato systems are available in three ... Systems Series. ... All Staccato ...
Biology Products: