Navigation Links
Genedata Screener Supports Small Molecule Research at the Broad Institute of Harvard and MIT

Screener's High Throughput Screening Capabilities Yield High-quality Data for the Broad Institute's NIH-funded Molecular Libraries and Imaging Initiative

Lexington, Mass. (USA) and Basel, Switzerland (PRWEB) October 6, 2009 -- Genedata, a leading provider of in silico solutions for pharmaceutical R&D and related life sciences, today announced that the Broad Institute of Harvard and MIT has adopted Genedata Screener® for small-molecule screening, which is integral to the Institute's contribution to the Molecular Libraries and Imaging Initiative funded by the National Institute of Health (NIH). This NIH program for medical research, comprised of nine institutions, conducts high-throughput biological studies of diverse small molecules to advance new drug discoveries.

"We're screening upwards of 50 assays and analyzing more than 20 million wells of screening data," explained Dave DeCaprio, associate director of the Chemical Biology Platform at the Broad Institute. "Our team evaluated a number of systems and found Genedata to enable the kind of massively high-throughput screening and high-quality data analyses that we need."
Screening Times Reduced to Days
DeCaprio's team is using Screener's Assay Analyzer and Condoseo modules. Providing analysis from a single plate to an entire screening campaign, Assay Analyzer captures data from diverse plate readers and processes them based on predefined business rules. Condoseo fits thousands of dose-response curves within minutes for efficient IC50 determination in validation and assay panel screens. According to DeCaprio, screening campaigns that once took several weeks to execute can now be done in days, due in large part to Screener's ease-of-use, advanced visualization, and statistical rigor.

"Screener's interactive visualization capabilities enable our screeners to analyze their own data, eliminating the need for them to involve a separate informatics group," said DeCaprio. "Now, our informatics group can focus on more strategic issues while screeners use their time more efficiently without having to shift between projects. Moreover, Genedata's high-quality data analyses and the confidence we have in those data enable us to focus on meta data analyses. Now, we focus on the larger issues aimed at designing new compound libraries and applying them in new kinds of biology."

"The Broad Institute is one of the world's leading research facilities and Dave's group is making a tremendous contribution to the public domain's knowledge on small molecules," said Dr. Othmar Pfannes, CEO of Genedata. "We're honored to have Genedata Screener used in this phase of early-stage drug discovery, which will drive new medicines in fighting psychiatric disease, cancer, infectious disease, and diabetes."

About Genedata
Genedata develops and globally markets sophisticated computational solutions for drug discovery and related research processes in the life sciences. Genedata's solutions enable scientists to process, integrate, analyze, and manage large and complex experimental data sets generated by high throughput technologies. Solutions include Genedata Phylosopher® for target discovery and integrative biological data management, Genedata Screener® for automated high throughput screening and high content screening, and Genedata Expressionist® for biomarker discovery and personalized medicine. Founded in 1997, Genedata is privately held, with headquarters in Basel, Switzerland, and offices in Boston & San Francisco, USA, Konstanz & Munich, Germany and Tokyo, Japan. For more information, please visit

The statements in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including risks associated with uncertainties related to contract cancellations, developing risks, competitive factors, uncertainties pertaining to customer orders, demand for products and services, development of markets for the Company's products and services. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to release publicly the result of any revisions to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.

All product and service names mentioned are the trademarks of their respective companies.


Read the full story at

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Related biology technology :

1. Genedata Expressionist with New Transcriptomics Biomarker Capabilities Advances Drug Development for Personalized Medicine
2. Genedata Launches Expressionist with Expanded Mass Spectrometry Biomarker Discovery Capabilities
3. AMERIGROUP Foundation Supports Groundbreaking on Grommet Island Park for People With Disabilities
4. Oncolytics Biotech(R) Inc. Announces Reovirus and Cisplatin Research Supports U.S. Phase 2 Metastatic Melanoma Trial
5. AEterna Zentaris: New Data Published on its Ghrelin Antagonist Compound, AEZS-123 (JMV2959), Supports its Use in Alcohol Addiction
6. San Diego Wireless Heavyweight Leap Wireless Supports New Start-up Incubator
7. Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrines Cotara(R) for the Treatment of Brain Cancer
8. Americas on the Waterway Supports US Oncology Foundation
9. Agendia Supports Genentechs Citizens Petition Urging FDA to Hold In-Vitro Diagnostic Tests to One Set of Scientific and Regulatory Standards
10. Pearson Foundation Supports Incoming LSU Biology Students With 21st Century Learning Tools
11. The Court Supports Bavarian Nordics Decision to Start Patent Infringement Case Against Oxford BioMedica
Post Your Comments:
(Date:10/13/2015)... the United States , ... represents about 14% of all new cases of kidney cancer.   ... Canada and Europe .  PRCC represents ... --> Hutchison China MediTech Limited ("Chi-Med") (AIM: HCM) today announces ... AB (publ) ("AstraZeneca") have completed enrolment in a global Phase II ...
(Date:10/12/2015)... 2015  MiMedx Group, Inc. (NASDAQ: MDXG ), ... and patent-protected processes to develop and market advanced products ... Sports Medicine, Ophthalmic, and the Dental sectors of healthcare, ... filed against the Company has been dismissed by the ... and CEO, stated, "As we suspected, this case was ...
(Date:10/12/2015)... 12, 2015 cell surface marker detection ... 2022, according to a new report by Grand View Research, ... in incidence of oncology diseases and other cell-associated disorders. ... to reach USD 6.49 billion by 2022, according to a ... demand can be attributed to rise in incidence of oncology ...
(Date:10/12/2015)... DIEGO , Oct. 12, 2015  Patara ... debilitating allergic and inflammatory diseases and conditions, today ... A preferred stock financing. Concurrent with the close ... entered into a Loan and Security Agreement with ... up to $7 million. Patara will use the ...
Breaking Biology Technology:
(Date:9/29/2015)... -- News facts: , ... , Minimized design shrinks PC footprint , ... embedded Fujitsu PalmSecure authentication enable enterprises to realize benefits ... that good things come in small packages, with the ... desktop and mobile portfolio. Featuring workplace design that favors ...
(Date:9/28/2015)... YORK , Sept. 28, 2015  The ... respiration rate and body temperature, is an essential ... can be indicators of deterioration in a patient,s ... hospital, vital signs are typically taken during routine ... hours. If a patient deteriorates between these observation ...
(Date:9/28/2015)... Synaptics Inc. (NASDAQ: SYNA ), the ... Lenovo has selected Synaptics , Natural ID ™ ... smartphone, the Vibe P1. The new Vibe P1 ... and provide swift access to applications and mobile payments ... FS4202 sensor solution utilizes AES256-bit encryption of the fingerprint ...
Breaking Biology News(10 mins):