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Genedata Screener Extends Support for High-Throughput Thermofluor Assays
Date:9/3/2013

Basel, Switzerland (PRWEB) September 03, 2013

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, today announced that the latest developments of Genedata Screener® will be shown in the European Laboratory Robotics Interest Group (ELRIG) 7th Annual Drug Discovery Conference. An ELRIG poster session will present a collaborative project with Bayer Pharma, which resulted in “A Novel Data Processing Workflow for Efficient Analysis of Large-Scale Thermofluor Assays.” Genedata Screener will also demonstrate its Compound Synergy and High Content Screening extensions during the ELRIG conference in Manchester, England (Booth F; Central Convention Centre; September 3-4).

The latest enhancements to Genedata Screener strengthen its capabilities as a premier data analysis platform for label-free technologies, in particular, enabling rapid assessment of a protein’s thermal stability under a variety of conditions. Using Genedata Screener, pharmaceutical companies can scale-up thermal shift assays and integrate them into existing screening data analysis workflows, reducing data analysis time from days to hours.

Thermal Shift Analysis Goes High-Throughput with Analysis Time Reduced by 80%
The Thermofluor assay, also referred to as Thermal Shift Analysis (TSA) or Differential Scanning Fluorimetry (DSF), is becoming widely-used for diverse applications in drug discovery, including: selection of suitable formulations for therapeutic antibodies; evaluation of additives and ligands for (co-) crystallization experiments; and identification of small molecule modulators of soluble targets and characterization of their binding mode. To run TSA in high-throughput, data analysis software
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