About sncRNAomics European Research Consortium
Novel anti-infectives are of high priority for global health care and sncRNAs in bacteria are an emerging class of new gene expression regulators, but their role in colonization and pathogenicity in largely unknown. The consortium brings together seven research groups from three countries to combine novel high-throughput sncRNA screening methods, whole-genome transcriptomics and proteomics and bioinformatics. These methods will be coupled with molecular characterization to provide new data regarding sncRNAs in major high-risk Grampositive microbes (e.g. Staphylococcus, Streptococcus, Enterococcus, Clostridium, and Listeria). Potential new drugs and diagnostic biomarkers will be validated using tissue culture and subsequently in in-vivo models. The sncRNAomics project is granted under the frame of the second multinational ERA-Net PathoGenoMics call. For more information, please visit www.pathogenomics-era.net/2ndJointCall.
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