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Gene Therapy Field Advances With Important Clinical Findings Reported in the New England Journal of Medicine
Date:2/3/2009

inuing advancement of gene therapy to wider applications remain strong. Ongoing and upcoming clinical trials will use safer designs of retroviral vectors, newer types of vectors for viral gene therapy, and emerging methods for direct in situ gene repair. These approaches to the treatment of hemoglobinopathies, hemophilia, muscular dystrophy, congenital retinopathies, neurodegenerative disorders, and other genetic diseases may further fulfill the promise that gene therapy made two decades ago."

"Historically, gene therapy has been long on promises and, all too often, short on clinical results. The success of this recent study marks an important milestone for the field, provides important insights into the use of advanced gene therapies, and sheds new light on the promise and new therapeutic realties of DNA-based approaches for the treatment of disease," stated Christopher J. Reinhard, Chairman and Chief Executive Officer of Cardium Therapeutics. "Cardium is developing a new class of growth factor biologics designed to take advantage of the body's own natural healing abilities for the regenerative treatment of ischemic conditions, such as chronic wounds, myocardial ischemia and heart attacks, and we look forward to completing our Phase 2b MATRIX gene therapy clinical trial that is evaluating the safety and efficacy of Excellarate for the potential treatment of non-healing diabetic foot ulcers."

About Cardium

Cardium Therapeutics, Inc. and its subsidiaries, InnerCool Therapies, Inc. and the Tissue Repair Company, are medical technology companies primarily focused on the development, manufacture and sale of innovative therapeutic products and devices for cardiovascular, ischemic and related indications.

Cardium's InnerCool Therapies subsidiary is a San Diego-based medical technology company in the emerging field of temperature modulation therapy to rapidly and controllably cool the body
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SOURCE Cardium Therapeutics
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