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Gene Therapy - Technologies, Markets and Companies
Date:11/30/2011

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Gene transfer for delivery of analgesics to the spinal nerve roots 304

Gene therapy of peripheral neuropathic pain 305

Gene transfer by injections into the brain substance 305

Targets for gene therapy of pain 306

Zinc finger DNA-binding protein therapeutic for chronic pain 306

Gene therapy for producing enkephalin to block pain signals 306

Targeting nuclear factor-?B 306

Gene therapy targeted to neuroimmune component of chronic pain 306

Potential applications of gene therapy for management of pain 307

Concluding remarks on gene therapy for pain 307

Gene therapy for psychiatric disorders 308

Gene therapy for depression 309

Gene therapy for enhancing cognition after stress 309

Gene therapy against fear disorders 309

Companies involved in gene therapy of neurological disorders 310

7. Gene Therapy of Cardiovascular Disorders 311

Introduction 311

Techniques of gene transfer to the cardiovascular system 311

Direct plasmid injection into the myocardium 312

Catheter-based systems for vector delivery 312

Ultrasound microbubbles for cardiovascular gene delivery 313

Vectors for cardiovascular gene therapy 313

Adenoviral vectors for cardiovascular diseases 313

Plasmid DNA-based delivery in cardiovascular disorders 313

Intravenous rAAV vectors for targeted delivery to the heart 314

Hypoxia-regulated gene therapy for myocardial ischemia 314

Angiogenesis and gene therapy of ischemic disorders 314

Therapeutic angiogenesis vs vascular growth factor therapy 315

Gene painting for delivery of targeted gene therapy to the heart 315

Gene delivery to vascular endothelium 316

Targeted plasmid DNA delivery to the cardiovascular system with nanoparticles 316

Vascular stents for gene delivery 316

Gene therapy for genetic cardiovascular disorders 317

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