Navigation Links
Gated STED -- developing the next generation of super-resolution microscopes
Date:11/11/2011

This release is available in German.

Leica Microsystems has signed an agreement with the Max Planck Society and the German Cancer Research Center (DKFZ) for the development of the next generation of super-resolution STED (Stimulated Emission Depletion) microscopy. This gives Leica Microsystems the license to develop the new technology, called gated STED, into a commercial product and put it on the market.

Stefan Hell, Director at the Max Planck Institute for Biophysical Chemistry, has taken his idea of STED microscopy a momentous step further with gated STED: The new technology significantly improves the resolution and contrast previously attained with CW-STED (Continuous-Wave Stimulated Emission Depletion) microscopy, while distinctly reducing laser intensity. This enhances photostability as well as live cell capability, substantially extending the range of possible applications. Also, gated STED technology will considerably increase the number of issues that can be addressed with STED fluorescence correlation spectroscopy (STED-FCS). The main application of gated STED technology will be the observation of molecule movements in the membrane of living cells.

The new product of Leica Microsystems will be launched in the first half of the year 2012. Thanks to Leica Microsystems' modular concept, the Leica TCS SP5 and Leica TCS STED CW confocal systems already on the market can be upgraded with gated STED.

"We're delighted to be able to continue the provenly successful cooperation with the Max Planck Society, its technology transfer organization Max Planck Innovation and the DKFZ with this trailblazing product development," says Stefan Traeger, Vice President of Leica Microsystems' Life Science Division. "The new gated STED microscope will enable us to further strengthen our technological lead in super-resolution microscopy especially for confocal systems."


'/>"/>
Contact: Markus Berninger
Markus.Berninger@Max-Planck-Innovation.de
49-892-909-1930
Max-Planck-Gesellschaft
Source:Eurekalert  

Related biology technology :

1. Retrospective Analysis of Phase 3 Data Suggest Wyeths Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms
2. Transgenomic Awarded SBIR Grant to Support Development of SURVEYOR(R) Endonuclease Adaptor-ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation
3. As personalized, genomic medicine takes off, four developing countries show the way for others
4. Napo Pharmaceuticals Will Provide Pediatric Formulation of Crofelemer at Cost to Developing Nations to Help Treat Life-Threatening Diarrhoel Diseases (Subject to FDA Approval)
5. BIO Ventures for Global Health Receives $7 Million Grant from Gates Foundation to Engage Biotechnology in the Fight Against Neglected Diseases of the Developing World
6. Frost & Sullivan Acknowledges ISTO Technologies Role in Developing Advanced Biologic Products for Bone Healing
7. MaxCyte Hosts Live Discussion with Industry Experts on the Challenges in Developing Cell-Based Screening Assays for Drug Discovery
8. Frost & Sullivan Recognizes ESBATechs Innovation in Developing Antibody Fragments for Biologic Therapeutics
9. Developing a Safer and More Effective Way to Deliver Rabies Antibodies
10. Schering-Plough Announces Collaboration With World Health Organization to Provide Access to Pandemic Influenza Vaccine Technology to Developing Countries
11. Immtech and Beijing Pharmaceutical Group Co. Sign Memorandum of Understanding to Explore Developing Strategic Business Alliance
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gated STED -- developing the next generation of super-resolution microscopes
(Date:10/11/2017)... ... October 11, 2017 , ... The CRISPR-Cas9 ... overexpression experiments and avoiding the use of exogenous expression plasmids. The simplicity of ... performing systematic gain-of-function studies. , This complement to loss-of-function studies, such as ...
(Date:10/11/2017)...  VMS BioMarketing, a leading provider of patient support solutions, ... Educator (CNE) network, which will launch this week. The VMS ... care professionals to enhance the patient care experience by delivering ... health care professionals to help women who have been diagnosed ... ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology today announced ... to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B ... to cross the cell membrane and bind intracellular STAT3 and inhibit its function. ...
(Date:10/10/2017)... ... , ... Dr. Bob Harman, founder and CEO of VetStem Biopharma, Inc. ... The event entitled “Stem Cells and Their Regenerative Powers,” was held on August ... MPVM was joined by two human doctors: Peter B. Hanson, M.D., Chief of Orthopedic ...
Breaking Biology Technology:
(Date:5/23/2017)... -- Hunova, the first robotic gym for the rehabilitation and functional motor sense ... Genoa, Italy . The first 30 robots will be available ... USA . The technology was developed and patented at the IIT ... Movendo Technology thanks to a 10 million euro investment from entrepreneur Sergio ... ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
(Date:4/11/2017)... April 11, 2017 Crossmatch®, a globally-recognized ... solutions, today announced that it has been awarded ... Projects Activity (IARPA) to develop next-generation Presentation Attack ... "Innovation has been a driving force within ... will allow us to innovate and develop new ...
Breaking Biology News(10 mins):