Navigation Links
Gastroenterologists Indicate They Are Increasingly Using Biologics to Treat Patients with Crohn's Disease in Remission than They Were One Year Ago, According to a Recent BioTrends Report

EXTON, Pa., March 5, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, although there have been no significant changes with regard to biologic treatment and Crohn's disease (CD) patients with active disease since 2012, surveyed gastroenterologist data indicate a significant 43 percent increase in biologic treatment among CD patients in remission since 2012, suggesting that biologic agents are increasingly prescribed to maintain the state of remission. The increase in biologic share among the CD patients in remission is most likely at the cost of 5-ASA treatment, which has experienced a 15 percent decline during the same time period, according to the surveyed gastroenterologists. Furthermore, Abbott's adalimumab (Humira) and UCB's certolizumab (Cimzia) are driving the escalation of biologic treatment among the remission population, with both agents experiencing significant patient share growth in this group over the past year.

(Logo: )

Although adalimumab and certolizumab are driving the escalation of biologic treatment among patients in remission, Janssen's infliximab (Remicade) remains the market leading biologic agent for the treatment of CD across all severities. More specifically, infliximab garners significantly more patient share, across all disease states, than any other CD treating biologic agent, followed by adalimumab then certolizumab. Though infliximab is used to treat a greater proportion of Crohn's patients across all severities, surveyed gastroenterologists equally value Humira with regard to preference, risk-benefit ratio and overall performance.

The recently published TreatmentTrends®: Crohn's Disease (US) report also reveals that three-quarters of the surveyed physicians feel that there is a high unmet need for new agents to treat Crohn's disease, often citing that they are challenged by the adverse events/side effects of current treatment and that achieving and maintaining remission and avoiding treatment failures are also issues. With regard to products in development, nearly one-third of gastroenterologists claim to be aware of products in development for the treatment of CD. Of those with unaided awareness of products in development, more than one-quarter noted Janssen's ustekinumab (Stelara), 22 percent specifically noted Takeda's vedolizumab and 22 percent noted Janssen's Simponi. When aided and asked which emerging agent will bring the most value to their practices, gastroenterologists are divided in opinion among vedolizumab, Stelara and Traficet-EN.

TreatmentTrends®: Crohn's Disease (US)  is an annual syndicated primary market research report series that provides a comprehensive view of the current and expected future management of CD, with a focus on biologic treatment. The survey was fielded in February.  The study included 91 board-certified gastroenterologists. TreatmentTrends®: Crohn's Disease (US) covers treatment approaches, including the use of pharmacotherapy for the treatment of CD, as well as attitudes and perceptions toward the biologic agents, advantages and disadvantages of these agents, ideal patient types, barriers to growth, and expected future use. In addition, respondents were queried about their awareness of and interest in products in development for the treatment of CD.About BioTrends Research Group
BioTrends Research Group provides syndicated and custom primary market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please contact us at (610) 321-9400 or BioTrends is a Decision Resources Group company.

About Decision Resources Group
Decision Resources Group is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources Group at

All company, brand, or product names contained in this document may be trademarks of their respective holders.For more information, contact:BioTrends Research Group Decision Resources GroupLynn Price  

Christopher Comfort610-321-9425

SOURCE BioTrends Research Group
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Big Pharma and Universities Increasingly Work to Advance Life Science Knowledge by Forming Strategic Partnerships, Public-Private Partnerships, and Open Innovation Programs: Pharmaceutical Research Collaborations Summit
2. Probiotic Action Comments on New Findings on Using Light Therapy to Fight Acne
3. Is Stress Causing Breakouts? Probiotic Action Sheds Light on an Article by the Huffington Post on if Acne and Stress are Still Related
4. Modeling Alzheimers disease using iPSCs
5. Using 3-D printing and injectable molds, bioengineered ears look and act like the real thing
6. Probiotic Action Discusses Using Social Media to Teach the Public about Acne
7. Forging a new periodic table using nanostructures
8. Probiotic Action Exposes 4 Items You Didn't Know were Causing Breakouts
9. Using single quantum dots to probe nanowires
10. Rigku Publishes New Method for Quantitative Analysis of Cast Iron Using the ZSX Primus III+
11. PNNL awarded $2.8 million to keep troops cool while using less fuel
Post Your Comments:
(Date:6/23/2016)... A person commits a crime, and the detective ... the criminal down. An outbreak of foodborne illness ... (FDA) uses DNA evidence to track down the bacteria that ... It,s not. The FDA has increasingly used a complex, cutting-edge ... illnesses. Put as simply as possible, whole genome sequencing is ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... ... June 23, 2016 , ... Velocity Products, a division of ... and optimized exclusively for Okuma CNC machining centers at The International Manufacturing Technology ... among several companies with expertise in toolholding, cutting tools, machining dynamics and distribution, ...
Breaking Biology Technology:
(Date:5/24/2016)... , May 24, 2016 Ampronix facilitates superior patient care by providing ...  3D medical LCD display is the latest premium product recently added to the range ... ... ... Sony 3d Imaging- LCD Medical Display- Ampronix News ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a ... the MegaMatcher Automated Biometric Identification System (ABIS) ... large-scale multi-biometric projects. MegaMatcher ABIS can process multiple ... using any combination of fingerprint, face or iris ... MegaMatcher SDK and MegaMatcher Accelerator , ...
(Date:4/19/2016)... The new GEZE SecuLogic access ... "all-in-one" system solution for all door components. It can ... door interface with integration authorization management system, and thus ... minimal dimensions of the access control and the optimum ... offer considerable freedom of design with regard to the ...
Breaking Biology News(10 mins):