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Gastroenterologists Indicate They Are Increasingly Using Biologics to Treat Patients with Crohn's Disease in Remission than They Were One Year Ago, According to a Recent BioTrends Report
Date:3/5/2013

EXTON, Pa., March 5, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, although there have been no significant changes with regard to biologic treatment and Crohn's disease (CD) patients with active disease since 2012, surveyed gastroenterologist data indicate a significant 43 percent increase in biologic treatment among CD patients in remission since 2012, suggesting that biologic agents are increasingly prescribed to maintain the state of remission. The increase in biologic share among the CD patients in remission is most likely at the cost of 5-ASA treatment, which has experienced a 15 percent decline during the same time period, according to the surveyed gastroenterologists. Furthermore, Abbott's adalimumab (Humira) and UCB's certolizumab (Cimzia) are driving the escalation of biologic treatment among the remission population, with both agents experiencing significant patient share growth in this group over the past year.

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Although adalimumab and certolizumab are driving the escalation of biologic treatment among patients in remission, Janssen's infliximab (Remicade) remains the market leading biologic agent for the treatment of CD across all severities. More specifically, infliximab garners significantly more patient share, across all disease states, than any other CD treating biologic agent, followed by adalimumab then certolizumab. Though infliximab is used to treat a greater proportion of Crohn's patients across all severities, surveyed gastroenterologists equally value Humira with regard to preference, risk-benefit ratio and overall performance.

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