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Galenea and Otsuka Pharmaceutical Extend & Expand Schizophrenia Research Collaboration
Date:10/5/2008

CAMBRIDGE, Mass. and TOKYO, Oct. 6 /PRNewswire/ -- Galenea Corp. and Otsuka Pharmaceutical Co., Ltd. announced today the extension and expansion of their research and development collaboration. The two companies have been working together since January 2005 to discover and develop novel therapies for schizophrenia and other central nervous system (CNS) diseases. The new agreement calls for a one year extension of the initial five-year alliance and brings the total committed funding for the collaboration to over $75 million.

Mark Benjamin, Chief Executive Officer of Galenea, said, "We are delighted that Otsuka has recognized the substantial progress made by Galenea over the last three years. This partnership is already producing some very exciting results that may one day lead to new and fundamentally better treatments for patients suffering from schizophrenia."

Galenea has made significant advances in several projects within the collaboration, including the progression of several molecules to the lead optimization stage. Each of these compounds represents a potential therapeutic with a novel mechanism of action for treating the impairments in memory and cognition common in schizophrenia and related disorders. With Otsuka's support, Galenea also recently completed the construction of state-of-the-art chemistry labs at their Cambridge facility, complementing their existing capabilities in neurobiology, electrophysiology, high-throughput screening and behavioral pharmacology.

"I am pleased that Otsuka has increased both the time and the resources dedicated to this collaboration," commented Professor Susumu Tonegawa, Ph.D., 1987 Nobel Prize winner in Medicine, professor at the Massachusetts Institute of Technology (MIT), Howard Hughes Medical Institute Investigator, Director of the RIKEN-Picower-MIT Center for Neural Circuit Genetics, and Galenea co-founder.

Otsuka will have exclusive worldwide rights to develop, manufacture and commer
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SOURCE Galenea Corp.
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