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GPCR Screening and Profiling Market Trends 2013 in New Research Report at ReportsnReports.com
Date:8/30/2013

anels used and total wells profiled per year at a fee-for-service providers; most trusted and most used providers of outsourced GPCR assay services; in house and outsourced budgets for GPCR screening and profiling; the breakdown of in house budgets; average costs paid per well for GPCR screening and profiling; level of interest in new assays/approaches for GPCR screening and profiling; suitability of available tools for new assays/approaches for GPCR screening and profiling; the proportion of GPCR assays that are made using primary cell lines and stem cell derived phenotypes; main barriers to the implementation of a new GPCR screening technology; where a GPCR reagent developer or assay fee-for-service provider should focus their efforts in the future; preferred way of sourcing GPCR expressing cell lines and the factors that drive decision making when sourcing; and any unmet needs in GPCR screening & profiling today.

The survey collected 96 validated responses, of these 66% provided comprehensive input. Survey responses were geographically split: 61% North America; 27% Europe; 7% Asia (excluding Japan); and 5% Japan.

Survey results were expressed as an average of all survey respondents. In addition, where appropriate the data was fully reanalyzed after sub-division into the following 5 survey groups: Pharma, Biotech, Academic Research, Europe and North America.

The median number of GPCR primary screening targets/programs under investigation in 2013 was 3.70% of GPCR primary screens were cell-based and 17% were orphan receptors in 2013.

The preferred GPCR readout technologies and suppliers for GPCR activation assays used in both primary screening and compound profiling were as follows: binding assays - radiometric from PerkinElmer; ß-arrestin recruitment or receptor internalization - chemiluminescence from DiscoveRx.

The preferred approach to GPCR profiling was to profile selected lead compounds only in the house. Median in
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