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Funding for Orphan Disease Indication Will Compare EpiVax's Tregitope with IVIG
Date:11/16/2012

rotein that is deficient in Pompe's disease, and a Phase II award to perform safety, toxicity and formulation studies on Tregitopes in the NOD model of Type 1 Diabetes.

About Tregitopes

Tregitopes are linear sequences of peptides contained within the framework of monoclonal antibodies and immunoglobulin-G ,which activate natural regulatory T cells. Tregitopes act as a natural 'off switch' and have been shown in standard preclinical models, and by collaborating laboratories, to suppress and treat autoimmune disease, allergies, and to effectively suppress the immunogenicity of co-administered proteins. This is a natural mechanism for suppressing tissue-destroying immune cells that are the root cause of 'organ-specific autoimmune diseases', in addition, modifying immune responses to biotherapeutics (such as FVIII and other biologics).

Tregitopes were discovered by the team of Anne S. De Groot and Bill Martin at EpiVax.

www.EpiVax.com

CONTACT:  Anthony Marcello, +1-401-272-2123, amarcello@epivax.com


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SOURCE EpiVax, Inc.
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