Navigation Links
Freeslate Collaborates with Medicines for Malaria Venture to Advance Therapeutic for Treating Malaria
Date:5/30/2013

SUNNYVALE, Calif (PRWEB) May 30, 2013

Freeslate, Inc., the leading provider of high throughput research solutions, today announced outcomes following a pro-bono study with researchers from Rutgers University in New Jersey working with Medicines for Malaria Venture (MMV, http://www.mmv.org) to discover new antimalarial agents. Using Freeslate’s CM3 Reaction Screening System, an efficient and simple resolution process that achieves near 100 percent chiral resolution was identified after just two weeks of effort with the Freeslate system. In follow up work at the Rutgers laboratories, the process performed extremely well on multi-gram scale and efficiently provides sufficient material to move the program forward toward the possible identification of a clinical candidate for malaria.

Freeslate will be offering a free webinar on this important study on June 25, 2013 (visit http://www.freeslate.com/news-events/upcoming-events to register).

"What remains amazing is the nature of the data generated by the Freeslate group using their CM3 system after just a couple of weeks of effort. It pointed to a process that immediately translated to gram and multi-gram scale. With only minor modifications, the data provided using the Freeslate system affords material with close to 100 percent chiral purity in near quantitative yield. Having worked on this problem in our laboratories for some time, it is clear we would not have been able to advance as quickly or at all without the collaboration with Freeslate," said David Floyd, a consultant with Medicines for Malaria Venture and Visiting Scientist at Rutgers University. "This procedure will allow us to efficiently prepare larger amounts of intermediate required to progress our program toward a possible clinical candidate.”

Malaria continues to cause over 600,000 deaths every year. MMV has a mission to reduce the burden of malaria in disease-endemic countries by discovering, developing, and facilitating delivery of new, effective, and affordable antimalarial drugs.

In March 2013, the researchers began working with Freeslate to leverage very preliminary data from the Rutgers labs using the Freeslate CM3 Reaction Screening System, an automated and configurable robotic platform that enables users to perform high-throughput process research and development (PRD). The research conducted on the System quickly provided the Rutgers researchers with conditions that, when scaled-up, proved to be simple, extremely efficient, and potentially cost-effective – a very important component to success with the discovery of new treatments for malaria.

“We were extremely excited about the opportunity to be a part of advancing this important malaria research program and are pleased that our existing product could contribute to their efforts in such a significant manner,” said John S. Senaldi, President and CEO of Freeslate. “The ability to go from preliminary work to a potentially scalable process in just two weeks demonstrates the true innovation and efficiency that our platform offers.”

With the CM3-based Reaction Screening System users can screen hundreds of experimental conditions per day under a variety of composition variables (e.g., acids, bases, counterions, catalysts, ligands, solvents) and under a variety of conditions (e.g., temperature, pressure, concentration, equivalents) to quickly optimize process parameters using minimal amounts of materials. Because of the greater throughput, users can explore experimental parameters outside those used in conventional approaches, reducing development risk, and allowing for non-intuitive discoveries.

About Freeslate

Freeslate is a privately held company that provides products and related services for high throughput research. Based on its proprietary laboratory automation platforms, high throughput pressure reactors, and integrated Lab Execution and Analysis (LEA) software suite, the company enables dramatic gains in its customers’ productivity and innovation by delivering seamlessly integrated automation solutions. Freeslate leverages its scientific expertise through its team of Ph.D. scientists, engineers, and software developers with directly relevant experience in the industries it serves. Collaborating with customers for more than a decade, the business has provided high throughput research solutions for the pharmaceutical, chemical, and energy industries. The company is headquartered in Sunnyvale, California, with direct sales and service in North America, Europe, and Asia. For more information, visit http://www.freeslate.com.

Read the full story at http://www.prweb.com/releases/2013/5/prweb10781883.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. OvaGene Oncology Collaborates With Moffitt Cancer Center to Develop and Commercialize microRNAs Associated With Chemotherapeutic Drug Response
2. Elsevier Collaborates with the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)
3. Elsevier Collaborates With Prophecy Healthcare to Enhance Its Staff Development Offerings for Healthcare Organizations
4. Goddard collaborates with international partners on MMS instrument
5. Ambrx Collaborates with Merck to Design and Develop Biologic Drug Conjugates
6. uniQure Collaborates with UCSF on GDNF Gene Therapy in Parkinsons Disease
7. Genetics Policy Institute (GPI) Collaborates on Second Midwest Conference on Stem Cell Biology and Therapy, Oct. 5-7 at Oakland University
8. Elsevier Collaborates With Infocomm Development Authority of Singapore and Top Academic Institutions to Bring CodeForScience to Singapore
9. DuPont Collaborates with Agricultural Educators to Reach More Students
10. DuPont Tate & Lyle Bio Products Collaborates with RML Incorporated to Develop Bio-Based Solution for Personal Care Products
11. Alliance for Safe Biologic Medicines Chairman Urges FDA to Ensure that Patient Safety is the Cornerstone of Biosimilar Pathway
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks Associates ... will speak at the TMA 2017 Annual Meeting , October 11 ... in the residential home security market and how smart safety and security ... Parks Associates: ... "The residential security ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... recipients of 13 prestigious awards honoring scientists who have made ... in a scheduled symposium during Pittcon 2018, the world’s leading conference and exposition ...
(Date:10/9/2017)... ... 09, 2017 , ... At its national board meeting in North Carolina, ... University’s Departments of Physics and Astronomy, has been selected for membership in ARCS ... for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the accelerating ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... advanced instruments and applications consulting for microscopy and surface analysis, Nanoscience Instruments ... consulting, Nanoscience Analytical offers a broad range of contract analysis services for ...
Breaking Biology Technology:
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/17/2017)... MELBOURNE, Florida , April 17, 2017 ... security technology company, announces the filing of its 2016 Annual Report ... Securities and Exchange Commission. ... Report on Form 10-K is available in the Investor Relations section ... well as on the SEC,s website at http://www.sec.gov . ...
Breaking Biology News(10 mins):